Ingul Charlotte Bjork, Tjonna Arnt Erik, Stolen Tomas Ottemo, Stoylen Asbjorn, Wisloff Ulrik
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Olav Kyrresgt. 9, Trondheim, Norway.
Arch Pediatr Adolesc Med. 2010 Sep;164(9):852-9. doi: 10.1001/archpediatrics.2010.158.
To measure cardiac function before and after 3 months of aerobic interval training in obese adolescents and to compare the findings with those in lean counterparts.
Exercise intervention study. Cardiac function was assessed by echocardiography and maximal oxygen uptake by ergospirometry.
The obese adolescents were referred from general practice to the St Olav University Hospital, Trondheim, Norway, and the control group was recruited from 2 schools.
Ten obese adolescents (mean [SD] age, 14.8 [1.2] years; mean [SD] body mass index {BMI; calculated as weight in kilograms divided by height in meters squared}, 33.5 [4.3]) and 10 lean counterparts (mean [SD] age, 14.9 [1.3] years; mean [SD] BMI, 20.4 [3.0]) participated. Intervention Aerobic interval training (4 x 4 minutes at 90% of maximal heart rate, 40 minutes of training in total) was performed twice per week for 13 weeks among the obese adolescents, whereas the lean counterparts only performed the tests.
Left ventricular end-diastolic volume, stroke volume, and maximal oxygen uptake.
Maximal oxygen uptake was 41.4% lower among the obese adolescents compared with the lean counterparts, but the maximal oxygen uptake increased by 8.6% (P = .008) after intervention. Obese adolescents initially had 7.8% and 14.5% lower left ventricular end-diastolic and stroke volumes, 21.3% reduced global strain rate and 16.3% global strain, reduced mitral annulus excursion and systolic/diastolic tissue velocity, longer isovolumic relaxation time, and longer deceleration time compared with the lean counterparts. No group difference was observed after the intervention. Aerobic interval training increased the ejection fraction but was lower compared with the lean counterparts. Aerobic interval training reduced fat content by 2.0% (P = .005) among the obese adolescents.
Aerobic interval training almost restored an impaired systolic and diastolic cardiac function among obese adolescents when compared with lean counterparts. These results may have implications for future treatment programs for obese adolescents.
测量肥胖青少年进行3个月有氧间歇训练前后的心脏功能，并将结果与瘦体重青少年进行比较。
运动干预研究。通过超声心动图评估心脏功能，通过运动心肺功能测试评估最大摄氧量。
肥胖青少年由普通诊所转诊至挪威特隆赫姆的圣奥拉夫大学医院，对照组从2所学校招募。
10名肥胖青少年（平均[标准差]年龄，14.8[1.2]岁；平均[标准差]体重指数{BMI；计算方法为体重（千克）除以身高（米）的平方}，33.5[4.3]）和10名瘦体重青少年（平均[标准差]年龄，14.9[1.3]岁；平均[标准差]BMI，20.4[3.0]）参与。干预措施：肥胖青少年每周进行两次有氧间歇训练（以最大心率的90%进行4次4分钟训练，共40分钟训练），持续13周，而瘦体重青少年仅进行测试。
左心室舒张末期容积、每搏输出量和最大摄氧量。
与瘦体重青少年相比，肥胖青少年的最大摄氧量低41.4%，但干预后最大摄氧量增加了8.6%（P = 0.008）。与瘦体重青少年相比，肥胖青少年最初的左心室舒张末期容积和每搏输出量分别低7.8%和14.5%，整体应变率降低21.3%，整体应变降低16.3%，二尖瓣环位移和收缩期/舒张期组织速度降低，等容舒张时间延长，减速时间延长。干预后未观察到组间差异。有氧间歇训练增加了射血分数，但仍低于瘦体重青少年。有氧间歇训练使肥胖青少年的脂肪含量降低了2.0%（P = 0.005）。
与瘦体重青少年相比，有氧间歇训练几乎恢复了肥胖青少年受损的收缩和舒张心脏功能。这些结果可能对肥胖青少年未来的治疗方案有影响。
