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坐位蹬车运动时左心室功能的超声心动图研究(作者译)

[Echocardiographic study of left ventricular performance during sitting bicycle exercise (author's transl)].

作者信息

Corallo S, Broso G, Pirastu A, Sega R, Bozzi G, Garimoldi M, Ravagnan S, Castelfranco M

出版信息

G Ital Cardiol. 1981;11(8):1072-82.

PMID:7327323
Abstract

Twelve healthy volunteers, mean age 25.4 +/- 4.18 years, performed sitting bicycle ergometer graded exercise to exhaustion. Recordings of left ventricular echocardiographic dimension, heart rate, arterial blood pressure, were obtained at rest and at two minutes intervals during exercise and recovery. Echocardiographic tracings were digitized and the values of three complexes were combined and means determined for the overall analysis. Heart rate increased from 76.92 +/- 15.09 to 154.91 +/- 12.13 (p less than 0.001) at peak exercise and decreased to 98.50 +/- 11.60 (P less than 0.001) at six minutes recovery. Similarly behaved blood pressure. End diastolic Echo dimension varied significantly from 46.50 +/- 4.66 mm to 51.44 +/- 5.38 mm (P less than 0.005) at peak exercise and to 45.91 +/- 4.52 mm (P less than 0.005) at six minutes recovery, but resulted unchanged at lower levels of exercise. It started to return towards resting values, from two to four minutes of recovery. End systolic dimension did not change significantly at any heart rate. Shortening fraction increased progressively and significantly at every step of exercise, decreasing in the same way during recovery: rest 38.42 +/- 3.62%; peak exercise 44.28 +/- 5.32% (P less than 0.005); end recovery 39.28 +/- 5.89% (P less than 0.001). So did respectively: Stroke volume (Teichholtz) 69.50 +/- 12.16 cc; 84.92 +/- 24.14 cc (P less than 0.005); 67.64 +/- 16.48 cc (P less than 0.005). Cardiac output 5.27 +/- 1.18 lt/min; 12.46 +/- 3.83 (P less than 0.001); 6.25 +/- 1.00 (P less than 0.005). Ejection fraction 68.33 +/- 4.68%, 78.58 +/- 8.80 (P less than 0.001); 68.82 +/- 8.16 (P less than 0.005). Mean normalized velocity of circumferential fibre shortening 1.33 +/- 0.25 circ/sec; 2.37 +/- 0.33 (P less than 0.001); 1.55 +/- 0.031 (P less than 0.001). These results indicate that in untrained healthy subjects, variations of cardiac output during exercise and recovery depend mainly on heart rate and left ventricular fibre shortening rate. Severe exertion produces an increase of left ventricular dimension due to a Frank-Starling effect. Sitting bicycle exercise Echocardiography appears to be a suitable method to assess Left ventricular performance with a chest position relevant to normal human conditions.

摘要

12名健康志愿者,平均年龄25.4±4.18岁,进行坐位自行车测力计递增运动直至力竭。在静息状态、运动期间及恢复过程中每隔两分钟记录左心室超声心动图尺寸、心率、动脉血压。对超声心动图描记图进行数字化处理,将三个心动周期的值合并,并确定平均值用于整体分析。运动峰值时心率从76.92±15.09增加到154.91±12.13(p<0.001),恢复6分钟时降至98.50±11.60(P<0.001)。血压表现类似。舒张末期超声心动图尺寸在运动峰值时从46.50±4.66mm显著变化至51.44±5.38mm(P<0.005),恢复6分钟时变为45.91±4.52mm(P<0.005),但在较低运动水平时保持不变。从恢复2分钟到4分钟开始向静息值恢复。收缩末期尺寸在任何心率下均无显著变化。缩短分数在运动的每个阶段均逐渐且显著增加,恢复期间以相同方式降低:静息时38.42±3.62%;运动峰值时44.28±5.32%(P<0.005);恢复末期39.28±5.89%(P<0.001)。每搏输出量(Teichholtz法)分别为:69.50±12.16cc;84.92±24.14cc(P<0.005);67.64±16.48cc(P<0.005)。心输出量5.27±1.18升/分钟;12.46±3.83(P<0.001);6.25±1.00(P<0.005)。射血分数68.33±4.68%,78.58±8.80(P<0.001);68.82±8.16(P<0.

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