Tarn Mark D, Maneuski Dzmitry, Alexander Richard, Brown Nathaniel J, O'Shea Val, Pimlott Sally L, Pamme Nicole, Archibald Stephen J
Positron Emission Tomography Research Centre, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
Chem Commun (Camb). 2016 Jun 7;52(45):7221-4. doi: 10.1039/c6cc00660d. Epub 2016 Mar 31.
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [(68)Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.
我们展示了在基于二氧化硅的整体柱上使用小型化的Medipix正电子传感器来检测临床PET放射性示踪剂[(68)Ga]柠檬酸镓,以用于微流控质量控制。与传统的基于碘化钠的放射性高效液相色谱检测相比,该系统实现了远为优异的信噪比,并能实时可视化整体柱中的正电子。