呼吸机相关性肺炎的经验性抗生素治疗。
Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia.
机构信息
College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Ave., Suite 203, Memphis, TN 38632, USA.
Harrison School of Pharmacy, Auburn University, 1321 Walker Building, Auburn, AL 36849, USA.
出版信息
Antibiotics (Basel). 2013 Jul 4;2(3):339-51. doi: 10.3390/antibiotics2030339.
Abstract
Ventilator-associated pneumonia (VAP) is the most common infectious complication in the intensive care unit. It can increase duration of mechanical ventilation, length of stay, costs, and mortality. Improvements in the administration of empirical antibiotic therapy have potential to reduce the complications of VAP. This review will discuss the current data addressing empirical antibiotic therapy and the effect on mortality in patients with VAP. It will also address factors that could improve the administration of empirical antibiotics and directions for future research.
摘要
呼吸机相关性肺炎（VAP）是重症监护病房中最常见的感染性并发症。它会延长机械通气时间、住院时间、增加成本，并导致更高的死亡率。改善经验性抗生素治疗的管理可能会降低 VAP 的并发症发生率。本文将讨论目前关于经验性抗生素治疗和对 VAP 患者死亡率影响的相关数据，以及可以改善经验性抗生素管理的因素和未来研究方向。
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