Seago Susan, Stroberg Edana, Metting Austin
Baylor Scott & White Health, Temple, Texas.
Proc (Bayl Univ Med Cent). 2016 Apr;29(2):204-6. doi: 10.1080/08998280.2016.11929419.
We present a patient who had rheumatoid meningitis while on infliximab, a tumor necrosis factor alpha (TNF-α) inhibitor, which initially presented as transient ischemic attacks. Although our patient had been stable on infliximab for several years, her neurologic symptoms improved when her infliximab was held due to active infection and then recurred after reinitiation of therapy. Rheumatoid meningitis is exceedingly rare; however, there have been several other reports of rheumatoid meningitis developing in patients on TNF-α inhibitor therapy.
我们报告一名在使用肿瘤坏死因子α（TNF-α）抑制剂英夫利昔单抗期间发生类风湿性脑膜炎的患者，该病最初表现为短暂性脑缺血发作。尽管我们的患者使用英夫利昔单抗数年病情一直稳定，但因发生活动性感染停用英夫利昔单抗后，其神经症状有所改善，而重新开始治疗后症状又复发。类风湿性脑膜炎极为罕见；然而，已有其他几例关于TNF-α抑制剂治疗患者发生类风湿性脑膜炎的报告。
