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一名孕妇甲状腺功能减退症的不寻常表现,酷似妊娠滋养细胞肿瘤。

Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm.

作者信息

Aminimoghaddam Soheila, Karisani Narmin, Mazloomi Maryam, Rahimi Maryam

机构信息

Department of Obstetrics & Gynecology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

Department of Obstetrics & Gynecology, Shahid Akbar-Abadi Hospital, Iran University of Medical Sciences, Molavi Street, Tehran, Iran.

出版信息

Case Rep Oncol Med. 2016;2016:3154267. doi: 10.1155/2016/3154267. Epub 2016 Feb 29.

DOI:10.1155/2016/3154267
PMID:27034864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4789410/
Abstract

Hypothyroidism is a common health issue worldwide with varying clinical manifestations. We report a woman who experienced an incomplete abortion and undiagnosed hypothyroidism who was referred to the oncologist with the suspicion of metastatic gestational trophoblastic neoplasm (GTN). A 29-year-old woman with incomplete abortion was referred to an oncologist for possible GTN due to persistent active vaginal bleeding, an elevated beta human chorionic gonadotropin (hCG), abnormal cervical inspection exam, abnormal liver function tests, ovarian enlargement, ascites, and a pleural effusion. She was found to have hypothyroidism in further work-up. She was managed with thyroid hormone replacement therapy and her condition improved after 6 weeks. Complete resolution of the ovarian mass and pericardial and pleural effusion was achieved. This case describes an important experience; hypothyroidism should be considered in the differential diagnosis of any woman with an incomplete abortion presenting with an ovarian mass. Evaluation and correct diagnosis are important to prevent mismanagement.

摘要

甲状腺功能减退是一种在全球范围内常见的健康问题,临床表现各异。我们报告了一名经历不完全流产且甲状腺功能减退未被诊断出的女性,她因疑似转移性妊娠滋养细胞肿瘤(GTN)被转诊至肿瘤科医生处。一名29岁不完全流产的女性因持续活动性阴道出血、β人绒毛膜促性腺激素(hCG)升高、宫颈检查异常、肝功能检查异常、卵巢肿大、腹水和胸腔积液,被转诊至肿瘤科医生处,怀疑患有GTN。在进一步检查中发现她患有甲状腺功能减退。她接受了甲状腺激素替代治疗,6周后病情有所改善。卵巢肿块以及心包和胸腔积液完全消退。该病例描述了一次重要的经历;对于任何出现卵巢肿块的不完全流产女性,在鉴别诊断时都应考虑甲状腺功能减退。评估和正确诊断对于防止管理不当很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf8d/4789410/61d4e6eb3b3a/CRIONM2016-3154267.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf8d/4789410/4a6cf9c31c78/CRIONM2016-3154267.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf8d/4789410/61d4e6eb3b3a/CRIONM2016-3154267.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf8d/4789410/4a6cf9c31c78/CRIONM2016-3154267.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf8d/4789410/61d4e6eb3b3a/CRIONM2016-3154267.002.jpg

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Ovarian Hyperstimulation Caused by Gonadotroph Pituitary Adenoma--Review.促性腺激素垂体腺瘤引起的卵巢过度刺激——综述
Adv Clin Exp Med. 2015 Jul-Aug;24(4):695-703. doi: 10.17219/acem/25212.
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Ovarian hyperstimulation syndrome, the master of disguise?卵巢过度刺激综合征,伪装大师?
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Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole.自然妊娠合并侵袭性葡萄胎时的卵巢过度刺激综合征
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Prevalence of overt and subclinical thyroid dysfunction among pregnant women and its effect on maternal and fetal outcome.孕妇显性和亚临床甲状腺功能障碍的患病率及其对母婴结局的影响。
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