Das Anirban, Pratap Abhishek
Department of Pulmonary Medicine, Murshidabad Medical College, Berhampore, West Bengal 742101, India.
Department of Pulmonary Medicine, Medical College, Kolkata, West Bengal 700 073, India.
Case Rep Oncol Med. 2016;2016:5462380. doi: 10.1155/2016/5462380. Epub 2016 Feb 29.
Metastatic tumours of pleura are the most common malignant tumours causing malignant pleural effusion. Lungs are the most common primary sites. Primary pleural tumours are rarely seen and diffuse malignant mesothelioma is the most common malignant tumour of pleura. Primary malignant neuroendocrine tumour of pleura is not reported in the literature. Here, we report a rare case of primary malignant neuroendocrine tumour of pleura in a fifty-two-year-old, nonsmoker female who presented with right-sided pleural effusion and ipsilateral, dull aching chest pain. Clinical presentations of inflammatory lesions like tuberculous pleuritis and benign and malignant neoplasms of pleura are indistinguishable; hence, fluid cytology, pleural biopsy, and immunohistochemistry are necessary for exact tissue diagnosis of the tumours, which is mandatory for correct treatment and prognostic assessment.
胸膜转移性肿瘤是引起恶性胸腔积液最常见的恶性肿瘤。肺是最常见的原发部位。原发性胸膜肿瘤少见，弥漫性恶性间皮瘤是胸膜最常见的恶性肿瘤。胸膜原发性恶性神经内分泌肿瘤在文献中未见报道。在此，我们报告一例罕见的胸膜原发性恶性神经内分泌肿瘤，患者为52岁不吸烟女性，表现为右侧胸腔积液和同侧钝痛胸痛。结核性胸膜炎等炎症性病变以及胸膜的良性和恶性肿瘤的临床表现难以区分；因此，对于肿瘤的准确组织诊断，液体细胞学检查、胸膜活检和免疫组织化学是必要的，这对于正确的治疗和预后评估至关重要。
