Policarpo Mario, Longoni Valentina, Garofalo Pietro, Spina Paolo, Pia Francesco
ENT Department, University of Eastern Piedmont, 28100 Novara, Italy.
Pathology Department, University of Eastern Piedmont, 28100 Novara, Italy.
Case Rep Otolaryngol. 2016;2016:3785979. doi: 10.1155/2016/3785979. Epub 2016 Mar 13.
Myoepithelioma is an extremely rare tumour subtype and diagnosis is based on a wide variation of cellular morphology. FNAC specimens do not always suffice for a definitive differential diagnosis which depends on histology and immunohistochemistry of the lesion. Case Presentation. A 54-year-old female came to our attention with dysphagia and dyslalia of 6-month standing. Ear, Nose, and Throat (ENT) examination revealed a voluminous mass on the right portion of the base of her tongue, where postcontrast T2-weighted Magnetic Resonance Imaging (MRI) evidenced a hyperintense lesion. The fine-needle aspiration specimen taken for cytology was not diagnostic, as a differential diagnosis between myoepithelioma and a malignant neoplasm of the salivary glands necessitates parameters that cytology alone cannot provide. Therefore, the whole lesion was excised by diode laser through a transoral approach. Histology and immunohistochemistry of the completely excised lesion confirmed a myoepithelioma.
肌上皮瘤是一种极其罕见的肿瘤亚型，其诊断基于细胞形态的广泛变化。细针穿刺抽吸活检（FNAC）标本并不总是足以进行明确的鉴别诊断，这取决于病变的组织学和免疫组织化学检查。病例报告。一名54岁女性因持续6个月的吞咽困难和构音障碍前来就诊。耳鼻喉科（ENT）检查发现其舌根右侧有一个巨大肿块，增强后T2加权磁共振成像（MRI）显示为高信号病变。用于细胞学检查的细针穿刺抽吸标本未能确诊，因为肌上皮瘤与唾液腺恶性肿瘤的鉴别诊断需要一些细胞学本身无法提供的参数。因此，通过经口入路用二极管激光切除了整个病变。对完全切除的病变进行组织学和免疫组织化学检查证实为肌上皮瘤。
