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先兆气味?偏头痛发作期间嗅觉幻觉(OHM)的临床特征

Scent of aura? Clinical features of olfactory hallucinations during a migraine attack (OHM).

作者信息

Mainardi Federico, Rapoport Alan, Zanchin Giorgio, Maggioni Ferdinando

机构信息

1 Headache Centre, Department of Neurology, SS. Giovanni e Paolo Hospital, Venice, Italy.

2 The David Geffen School of Medicine, UCLA, USA.

出版信息

Cephalalgia. 2017 Feb;37(2):154-160. doi: 10.1177/0333102416630580. Epub 2016 Jul 11.

Abstract

Introduction Olfactory hallucination during a migraine attack (OHM) is a rare phenomenon. At present, it is not considered a manifestation of migraine aura. Material and methods The clinical features of OHM were collected in 11 patients. Results Of the 11 patients, 10 had migraine without aura and one migraine with aura associated with OHM. Mean age at onset of headache and at appearance of OHM were respectively 17.8 and 32.3 years. Migraine average frequency was 3.9 attacks/month, 19% of them being associated with OHM. The temporal pattern of OHM maintained the same characteristics in the different attacks. OHM onset was described as sudden ( n = 5), gradual ( n = 3), initially sudden and then gradual ( n = 2), or developing in a few seconds ( n = 1). In most of the cases ( n = 8) OHM lasted from 3 to 10 minutes; it persisted during the pain phase (2-24 hours) in only three patients. The type of the perceived smell was invariably constant in nine patients. Conclusion OHM features fulfilled the ICHD-III beta criteria for typical aura.

摘要

引言 偏头痛发作期间的嗅觉幻觉(OHM)是一种罕见现象。目前,它不被视为偏头痛先兆的表现。

材料与方法 收集了11例OHM患者的临床特征。

结果 11例患者中,10例为无先兆偏头痛,1例为伴有OHM的有先兆偏头痛。头痛发作时和OHM出现时的平均年龄分别为17.8岁和32.3岁。偏头痛平均发作频率为每月3.9次,其中19%与OHM相关。OHM在不同发作中的时间模式保持相同特征。OHM发作被描述为突然发作(n = 5)、逐渐发作(n = 3)、起初突然发作然后逐渐发作(n = 2)或在几秒钟内出现(n = 1)。在大多数病例(n = 8)中,OHM持续3至10分钟;仅3例患者在疼痛期(2至24小时)持续存在。9例患者所感知气味的类型始终不变。

结论 OHM特征符合国际头痛疾病分类第三版(ICHD-III)β版中典型先兆的标准。

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