Yoneoka Yutaka, Kaku Shoji, Tsuji Shunichiro, Yamashita Hiroto, Inoue Takashi, Kimura Fuminori, Murakami Takashi
Department of Obstetrics and Gynecology, National Hospital Organization Higashi-Ohmi General Medical Center, 255 Gochi-cho, Higashiohmi, Shiga, 527-0044, Japan.
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
BMC Pregnancy Childbirth. 2016 Apr 1;16:70. doi: 10.1186/s12884-016-0855-6.
Vesicoureteral reflux is thought to predispose to urinary tract infection and renal scarring, and ureteral reimplantation in childhood remains the gold standard for its treatment. It has been reported that the risk of postrenal failure during pregnancy is increased among women with Politano-Leadbetter ureteral reimplantation. In previous case reports on patients with progressive hydronephrosis and renal failure during pregnancy after ureteral reimplantation, percutaneous nephrostomy was always required, so there has been no information about the clinical management of such patients by ureteral stenting. Here we report a patient with a history of bilateral ureteral reimplantation, in whom severe hydronephrosis during pregnancy was managed with ureteral stents.
A primigravida with severe hydronephrosis was referred to us at 29 weeks of gestation. Bilateral Politano-Leadbetter ureteral reimplantation had been performed at the age of 3 years. She was hospitalized immediately, and bilateral ureteral stents were successfully inserted. Post-obstructive diuresis occurred after the stents were placed. Urinary tract infection developed after removal of the urethral catheter 1 week later, but responded to antibiotic therapy and catheter replacement. Labor was induced at 39 weeks of gestation, with vaginal delivery of a healthy male infant. Both stents were found to have spontaneously migrated into the urethra after delivery. Repeat stenting under spinal anesthesia was required to improve postpartum symptoms of back pain and fever. Right distal ureteral obstruction persisted at 6 months after delivery and repeat ureteral reimplantation is planned.
General obstetricians will not necessarily pay attention to a history of Politano-Leadbetter ureteral reimplantation, but these patients should undergo careful monitoring of renal function and urinary tract morphology during perinatal care. In the present case, ureteral stenting was effective for postrenal failure during pregnancy after ureteral reimplantation. If ureteral stenting is selected, attention should be paid to post-obstructive diuresis, infection, and stent migration.
膀胱输尿管反流被认为易导致尿路感染和肾瘢痕形成,儿童期输尿管再植术仍是其治疗的金标准。据报道,接受波利塔诺-利德贝特输尿管再植术的女性孕期发生肾后性肾衰竭的风险增加。在先前关于输尿管再植术后孕期出现进行性肾积水和肾衰竭患者的病例报告中,总是需要进行经皮肾造瘘术,因此尚无关于此类患者输尿管支架置入临床管理的信息。在此,我们报告一例有双侧输尿管再植术病史的患者,其孕期严重肾积水通过输尿管支架得到处理。
一名初产妇在妊娠29周时因严重肾积水转诊至我院。其在3岁时接受了双侧波利塔诺-利德贝特输尿管再植术。她立即住院,双侧输尿管支架成功置入。支架置入后发生梗阻后利尿。1周后拔除尿道导管后发生尿路感染,但对抗生素治疗和更换导管有反应。妊娠39周时引产,经阴道分娩一名健康男婴。产后发现两个支架均自发迁移至尿道。需要在脊髓麻醉下再次置入支架以改善产后背痛和发热症状。产后6个月右侧输尿管远端梗阻持续存在,计划再次进行输尿管再植术。
普通产科医生不一定会关注波利塔诺-利德贝特输尿管再植术病史,但这些患者在围产期护理期间应接受肾功能和尿路形态的仔细监测。在本病例中,输尿管支架置入对输尿管再植术后孕期的肾后性肾衰竭有效。如果选择输尿管支架置入,应注意梗阻后利尿、感染和支架迁移。