Ko Yen Chen K, Farr Jeffrey B, Yoon Angela, Philipone Elizabeth
*Oral and Maxillofacial Pathology, Columbia University Medical Center, New York, NY; †Columbia University College of Dental Medicine, New York, NY; ‡Columbia University Medical Center, New York, NY; and §Oral Pathology, Faculty of Dental Medicine, Columbia University Medical Center, New York, NY.
Am J Dermatopathol. 2016 Jun;38(6):e68-71. doi: 10.1097/DAD.0000000000000461.
Gingival fibromatosis (GF) is a condition characterized by a progressive, normal colored enlargement of the gingiva caused by an increase in the size of submucosal connective tissue. Both familial and idiopathic variants of the condition exist. The authors present a case report of a 38-year-old African American man who presented with an impressive overgrowth of the maxillary and mandibular gingivae, subsequently diagnosed as idiopathic GF. In this report, the authors will review the etiologies, treatment, and clinical and histological findings of GF, review similar cases found in the literature, and discuss the differential diagnosis for diffuse gingival enlargements.
牙龈纤维瘤病（GF）是一种以牙龈进行性、颜色正常的肿大为特征的疾病，由黏膜下结缔组织大小增加所致。该疾病存在家族性和特发性两种类型。作者报告了一例38岁非裔美国男性病例，该患者上颌和下颌牙龈显著过度生长，随后被诊断为特发性GF。在本报告中，作者将回顾GF的病因、治疗以及临床和组织学表现，回顾文献中发现的类似病例，并讨论弥漫性牙龈肿大的鉴别诊断。
