Pandey Prasamsa, Al-Rohil Rami N, Goldstein Jennifer B, Tetzlaff Michael T, Barnes Tamara G, Baldwin Sarah E, Fogelman David, Abraham Susan C, Piha-Paul Sarina A
Departments of *Investigational Cancer Therapeutics, †Pathology, and ‡Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
Am J Dermatopathol. 2016 Nov;38(11):852-856. doi: 10.1097/DAD.0000000000000604.
Mucoepidermoid pancreatic cancer is a rare entity with only 8 cases reported in the literature. On review of the literature, the authors found that cutaneous metastases in pancreatic cancer are rare and have not been associated with the mucoepidermoid subtype. The authors present the first reported case of cutaneous metastasis in a patient with mucoepidermoid carcinoma of the pancreas.
A 50-year old white male with a metastatic invasive poorly differentiated mucoepidermoid carcinoma of the pancreas was found to have a slow growing lesion in the skin over his left upper quadrant while undergoing active therapy. The lesion was biopsied and the pathology was consistent with pancreatic origin sharing similar morphologic features when compared with the primary pancreactectomy specimen.
Mucoepidermoid pancreatic cancer is an exceedingly rare subtype of pancreatic cancer, with very little information regarding its diagnosis, treatment, and patterns of metastases. Here, the authors present the first reported case of cutaneous metastases of mucoepidermoid pancreatic cancer.
黏液表皮样胰腺癌是一种罕见的疾病，文献中仅报道了8例。在回顾文献时，作者发现胰腺癌的皮肤转移很少见，且与黏液表皮样亚型无关。作者报告了首例胰腺黏液表皮样癌患者发生皮肤转移的病例。
一名50岁的白人男性，患有转移性浸润性低分化胰腺黏液表皮样癌，在接受积极治疗时，发现左上腹皮肤有一个生长缓慢的病变。对该病变进行活检，病理结果与胰腺来源一致，与原发性胰腺切除标本相比，具有相似的形态学特征。
黏液表皮样胰腺癌是胰腺癌中极为罕见的一种亚型，关于其诊断、治疗和转移模式的信息非常少。在此，作者报告了首例胰腺黏液表皮样癌皮肤转移的病例。
