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肾母细胞瘤:成人患者中的罕见实体瘤

Wilms Tumor: An Uncommon Entity in the Adult Patient.

作者信息

Mahmoud Fade, Allen M Brandon, Cox Roni, Davis Rodney

机构信息

Assistant Professor of Medicine in the Department of Hematology and Oncology at the University of Arkansas for Medical Sciences in Little Rock.

Pathologist at the University of Arkansas for Medical Sciences in Little Rock.

出版信息

Perm J. 2016 Spring;20(2):e119-21. doi: 10.7812/TPP/15-110. Epub 2016 Mar 21.

Abstract

Wilms tumor, the most common kidney tumor in children, is rarely seen in adults, making it a challenge for the adult oncologist to diagnose and treat. Unlike with renal cell carcinoma, patients with Wilms tumor should receive adjuvant chemotherapy with or without radiation therapy. Adult oncologists may not be familiar with pediatric oncology protocols, so it is important to consult with pediatric oncologists who have more experience in this disease. Multimodal therapy based on pediatric protocols improved the outcomes of adults with Wilms tumor worldwide. We report a rare case of a 24-year-old woman with a slow-growing mass of the left kidney during a 4-year period. The mass was surgically removed and final diagnosis confirmed by pathology to be Wilms tumor. The patient received adjuvant chemotherapy and has been free of disease since 2014.

摘要

肾母细胞瘤是儿童最常见的肾脏肿瘤,在成人中很少见,这给成人肿瘤学家的诊断和治疗带来了挑战。与肾细胞癌不同,肾母细胞瘤患者无论是否接受放射治疗都应接受辅助化疗。成人肿瘤学家可能不熟悉儿科肿瘤学方案,因此咨询在该疾病方面更有经验的儿科肿瘤学家很重要。基于儿科方案的多模式治疗改善了全球成人肾母细胞瘤患者的治疗结果。我们报告了一例罕见病例,一名24岁女性在4年期间左肾有一个生长缓慢的肿块。该肿块通过手术切除,病理最终确诊为肾母细胞瘤。患者接受了辅助化疗,自2014年以来一直无病生存。

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