Akinbodewa A A, Adejumo O A, Ogunsemoyin A O, Osasan S A, Adefolalu O A
Kidney Care Centre, University of Medical Sciences, Ondo State, Nigeria.
Ann Afr Med. 2016 Apr-Jun;15(2):83-6. doi: 10.4103/1596-3519.179735.
A little over 30 cases on co-existing nephrotic syndrome and autosomal dominant polycystic kidney disease (ADPKD) have been reported from different regions of the world since 1957. We present a case report on co-existence of nephrotic syndrome (secondary to lupus nephritis) with ADPKD in a 24-year-old woman from Nigeria. She was positive for anti-double stranded DNA. Renal histology showed International Society of Nephrology/Renal Pathology Society Class II lupus nephritis. The co-existence of nephrotic syndrome and ADPKD may have been overlooked in Africa in the past. There is a need to screen for nephrotic syndrome in patients with ADPKD among clinicians in the African setting.
自1957年以来，世界各地已报道了30多例同时患有肾病综合征和常染色体显性多囊肾病（ADPKD）的病例。我们报告了一名来自尼日利亚的24岁女性，她同时患有肾病综合征（继发于狼疮性肾炎）和ADPKD。她的抗双链DNA检测呈阳性。肾脏组织学检查显示为国际肾脏病学会/肾脏病理学会II级狼疮性肾炎。过去，肾病综合征和ADPKD的并存情况在非洲可能被忽视了。在非洲地区的临床医生中，有必要对ADPKD患者进行肾病综合征筛查。
