Andrews S, Hernandez E, Miyazawa K
Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii.
Obstet Gynecol. 1989 May;73(5 Pt 1):747-50.
Between February 1985 and April 1988, 360 women were seen at Tripler Army Medical Center's cervical clinic as part of a prospective study to assess the value of paired Papanicolaou smears in the follow-up of atypical squamous cells in a cervical cytologic smear. The evaluation consisted of paired repeat Papanicolaou smears and colposcopy. Colposcopically directed biopsies and/or endocervical curettage were performed in 86% of the subjects. The results of the paired Papanicolaou smears were negative/negative in 202 patients (56%). Cervical intraepithelial neoplasia was diagnosed histopathologically in 16% of all patients and in 10% of those with negative/negative repeat smears. We conclude that the presence of atypical squamous cells in a Papanicolaou smear should be considered abnormal and that colposcopy and colposcopically directed biopsies should be performed for these patients.
1985年2月至1988年4月期间，360名女性在特里普勒陆军医疗中心的宫颈诊所接受检查，这是一项前瞻性研究的一部分，旨在评估成对巴氏涂片在宫颈细胞学涂片中非典型鳞状细胞随访中的价值。评估包括成对重复巴氏涂片和阴道镜检查。86%的受试者接受了阴道镜引导下的活检和/或宫颈管刮除术。成对巴氏涂片结果在202例患者中为阴性/阴性（56%）。所有患者中16%经组织病理学诊断为宫颈上皮内瘤变，重复涂片为阴性/阴性的患者中这一比例为10%。我们得出结论，巴氏涂片中出现非典型鳞状细胞应被视为异常，对于这些患者应进行阴道镜检查和阴道镜引导下的活检。
