Glotzbach S F, Tansey P A, Baldwin R B, Ariagno R L
Department of Pediatrics, Stanford University School of Medicine, CA 94305.
Pediatr Res. 1989 Mar;25(3):258-61. doi: 10.1203/00006450-198903000-00007.
Periodic breathing cycle duration (PCD), the time interval from the beginning of one respiratory pause to the beginning of the next pause within an episode of periodic breathing (PB), was measured by examination of 24-h impedance pneumograms in 51 preterm infants. Calculations of the SD of PCD within a given PB episode (approximately 3 s) and comparison of PCD values between two PB episodes in each infant (r = 0.68) revealed considerable variability in PCD. This variability was not related to the number of cycles in the PB episode or to the amount of PB in the recording. Contrary to the decrease in PCD from 15.0 s at 1 wk to 12.4 s at 12 wk in term infants reported previously, PCD did not vary as a function of postconceptional, gestational, or postnatal age in our preterm population. PCD has limited value as an indicator of chemoreceptor maturation in the preterm infant, and most likely reflects transient adjustments in respiratory system control.
周期性呼吸周期时长（PCD），即周期性呼吸（PB）发作期间从一次呼吸暂停开始到下一次暂停开始的时间间隔，通过对51例早产儿的24小时阻抗呼吸图进行检查来测量。计算给定PB发作内（约3秒）PCD的标准差，并比较每个婴儿两次PB发作之间的PCD值（r = 0.68），结果显示PCD存在显著变异性。这种变异性与PB发作中的周期数或记录中的PB量无关。与之前报道的足月儿PCD从1周时的15.0秒降至12周时的12.4秒不同，在我们的早产儿群体中，PCD并不随孕龄、胎龄或出生后年龄而变化。PCD作为早产儿化学感受器成熟指标的价值有限，很可能反映了呼吸系统控制的短暂调整。
