Glotzbach S F, Baldwin R B, Lederer N E, Tansey P A, Ariagno R L
Department of Pediatrics, Stanford University School of Medicine, California 94305.
Pediatrics. 1989 Nov;84(5):785-92.
The prevalence and characteristics of periodic breathing in preterm infants were measured by 24-hour impedance pneumograms in 66 preterm infants before discharge from the nursery. Four periodic breathing parameters (percentage of periodic breathing per quiet time, number of episodes of periodic breathing per 100 minutes of quiet time, mean duration of periodic breathing, and longest episode of periodic breathing) were compared to data available from healthy term infants and from term infants who subsequently died of sudden infant death syndrome (SIDS). Periodic breathing was found in all preterm infants studied and mean periodic breathing parameter values (12.0%, 8.6 episodes, 1.2 minutes, and 7.3 minutes, respectively) in our preterm population were substantially higher than values from healthy term infants and SIDS victims. Most periodic breathing parameters decreased significantly in infants studied at 39 to 41 weeks' postconceptional age compared with earlier postconceptional age groups. No relationship was found between central apneas of greater than or equal to 15 seconds' duration and postconceptional age or any periodic breathing parameter. Periodic breathing is a common respiratory pattern in preterm infants that is usually not of pathologic significance. Associations between elevated levels of periodic breathing and respiratory dysfunction or SIDS should be made with caution.
通过对66名早产儿在保育室出院前进行24小时阻抗呼吸描记图测量，来测定早产儿周期性呼吸的患病率及特征。将四个周期性呼吸参数（每安静时间内周期性呼吸的百分比、每100分钟安静时间内周期性呼吸发作次数、周期性呼吸的平均持续时间以及最长周期性呼吸发作时间）与健康足月儿以及随后死于婴儿猝死综合征（SIDS）的足月儿的现有数据进行比较。在所研究的所有早产儿中均发现了周期性呼吸，我们的早产儿群体中周期性呼吸参数的平均值（分别为12.0%、8.6次发作、1.2分钟和7.3分钟）显著高于健康足月儿和SIDS受害者的值。与较早的孕龄组相比，孕龄39至41周时研究的婴儿的大多数周期性呼吸参数显著降低。未发现持续时间大于或等于15秒的中枢性呼吸暂停与孕龄或任何周期性呼吸参数之间存在关联。周期性呼吸是早产儿常见的呼吸模式，通常无病理意义。周期性呼吸水平升高与呼吸功能障碍或SIDS之间的关联应谨慎判断。
