Kang Joon Young, Kim Ryunhyung, Kim Hyunsun, Kang Yeonjune, Hahn Susan, Fu Zhengrui, Khalid Mamoon I, Schenck Enja, Thesen Thomas
Department of Neurology, New York University School of Medicine.
Department of Electrical Engineering, New York University.
Stud Health Technol Inform. 2016;220:167-70.
The prevalence of autism spectrum disorder (ASD) has risen significantly in the last ten years, and today, roughly 1 in 68 children has been diagnosed. One hallmark set of symptoms in this disorder are stereotypical motor movements. These repetitive movements may include spinning, body-rocking, or hand-flapping, amongst others. Despite the growing number of individuals affected by autism, an effective, accurate method of automatically quantifying such movements remains unavailable. This has negative implications for assessing the outcome of ASD intervention and drug studies. Here we present a novel approach to detecting autistic symptoms using the Microsoft Kinect v.2 to objectively and automatically quantify autistic body movements. The Kinect camera was used to film 12 actors performing three separate stereotypical motor movements each. Visual Gesture Builder (VGB) was implemented to analyze the skeletal structures in these recordings using a machine learning approach. In addition, movement detection was hard-coded in Matlab. Manual grading was used to confirm the validity and reliability of VGB and Matlab analysis. We found that both methods were able to detect autistic body movements with high probability. The machine learning approach yielded highest detection rates, supporting its use in automatically quantifying complex autistic behaviors with multi-dimensional input.
在过去十年中,自闭症谱系障碍(ASD)的患病率显著上升,如今,大约每68名儿童中就有1人被诊断患有该病。这种疾病的一组标志性症状是刻板运动行为。这些重复性动作可能包括旋转、身体摇晃或拍手等。尽管受自闭症影响的人数不断增加,但仍没有一种有效、准确的自动量化此类动作的方法。这对评估ASD干预和药物研究的结果产生了负面影响。在此,我们提出一种新颖的方法,利用微软Kinect v.2来检测自闭症症状,以客观、自动地量化自闭症患者的身体动作。使用Kinect摄像头拍摄12名演员,每人表演三种不同的刻板运动行为。采用视觉手势构建器(VGB),运用机器学习方法分析这些录像中的骨骼结构。此外,在Matlab中进行了运动检测的硬编码。采用人工评分来确认VGB和Matlab分析的有效性和可靠性。我们发现这两种方法都能够以较高概率检测出自闭症患者的身体动作。机器学习方法的检测率最高,支持其用于通过多维输入自动量化复杂的自闭症行为。