Schajowicz F
J Bone Joint Surg Br. 1977 Nov;59-B(4):473-80. doi: 10.1302/0301-620X.59B4.270475.
The features are described of seven cases of "juxtacortical" chondrosarcoma, the term introduced by Jaffe for a rare but distinct entity and now accepted in the World Health Organisation classification as preferable to the term "periosteal" chondrosarcoma. In all cases the lesion involved the shaft of a long bone, most often the femur, and in two cases two different long bones were affected. Six of the seven patients were male and all were in the second decade. The characteristic appearance was that of a small tumour adjacent to the cortex with areas of spotty calcification often accompanied by radiating bone spicules perpendicular to the bone shaft and a typical Codman's triangle. Histologically all the tumours showed a cartilaginous lobular pattern, well limited on the surface and seldom infiltrating the cortex; areas of spotty calcification and enchondral ossification were often present but tumour osteoid and bone were conspicuously absent. Despite the ominous histological aspect, the prognosis proved to be relatively favourable compared with the usual central chondrosarcoma of a similar grade of malignancy.
本文描述了7例“皮质旁”软骨肉瘤的特征。“皮质旁”这一术语由贾菲提出，用于描述一种罕见但独特的实体，目前在世界卫生组织分类中被认为比“骨膜”软骨肉瘤这一术语更合适。所有病例中，病变均累及长骨干，最常见于股骨，2例累及两根不同的长骨。7例患者中有6例为男性，均处于第二个十年年龄段。其特征性表现为靠近皮质的小肿瘤，伴有散在钙化区域，常伴有垂直于骨干的放射状骨针和典型的科德曼三角。组织学上，所有肿瘤均呈软骨小叶模式，表面界限清楚，很少浸润皮质；常可见散在钙化区和软骨内成骨，但明显缺乏肿瘤类骨质和骨组织。尽管组织学表现不佳，但与恶性程度相似的常见中央型软骨肉瘤相比，预后相对较好。
