Putti T C, Kahn L B, Aprin H
Department of Pathology, Long Island Jewish Medical Center, New Hyde Park, NY, USA.
Arch Pathol Lab Med. 1997 Jan;121(1):70-4.
Periosteal chondrosarcoma occurs predominantly in the long tubular bones. The long-term survival rate is better and there are fewer local recurrences than with central chondrosarcoma. A case of periosteal chondrosarcoma is reported with a review of the literature. A 13-year-old girl presented with swelling of the distal right thigh of 3 weeks' duration. Radiographs and computed tomographic scan of the lesion showed a soft tissue mass, measuring 6 x 6 cm, with matrix calcification arising from the surface of the bone. An open biopsy followed by en bloc resection of the tumor was performed. The histologic features were those of a chondrosarcoma. An 8-year follow-up period has shown no local recurrence or distant metastases. The differential diagnosis of periosteal chondrosarcoma includes periosteal (chondroblastic) osteosarcoma and periosteal chondroma. Controversy exists as to whether periosteal chondrosarcoma is an entity distinct from periosteal osteosarcoma. The clinicopathologic features in this case and in the cases reported in the literature support the contention that periosteal chondrosarcoma is indeed distinct.
骨膜软骨肉瘤主要发生于长管状骨。与中央型软骨肉瘤相比，其长期生存率更高，局部复发率更低。本文报告1例骨膜软骨肉瘤病例并复习相关文献。一名13岁女孩因右大腿远端肿胀3周就诊。病变的X线片和计算机断层扫描显示一个6×6cm的软组织肿块，伴有从骨表面发出的基质钙化。进行了开放活检，随后整块切除肿瘤。组织学特征符合软骨肉瘤。8年的随访期显示无局部复发或远处转移。骨膜软骨肉瘤的鉴别诊断包括骨膜（软骨母细胞性）骨肉瘤和骨膜软骨瘤。骨膜软骨肉瘤是否为与骨膜骨肉瘤不同的独立实体存在争议。该病例及文献报道病例的临床病理特征支持骨膜软骨肉瘤确实不同的观点。
