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转移性卵巢癌所致炎性乳腺癌

Inflammatory Breast Cancer from Metastatic Ovarian Cancer.

作者信息

Achariyapota Vuthinun, Chuangsuwanich Tuenjai, Benjapibal Mongkol

机构信息

Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Bangkok 10700, Thailand.

Department of Pathology, Faculty of Medicine Siriraj Hospital, Bangkok 10700, Thailand.

出版信息

Case Rep Obstet Gynecol. 2016;2016:3476143. doi: 10.1155/2016/3476143. Epub 2016 Mar 7.

DOI:10.1155/2016/3476143
PMID:27047697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4800108/
Abstract

Metastases to the breast from tumors other than breast carcinomas are extremely rare and represent only 0.2-1.3% of all diagnosed malignant breast tumors. Furthermore, while the most common sites for advanced ovarian cancer metastases are the liver, lung, and pleura, metastasis to the breast from a primary ovarian cancer is uncommon and has only been reported in 0.03-0.6% of all breast cancers. Here we describe a case report of a 50-year-old female patient with a rare case of breast metastases from an advanced ovarian cancer, presenting as inflammatory breast cancer. Our observations emphasize the clinical importance of distinguishing between primary and metastatic breast cancer during diagnosis for the purpose of appropriate prognosis and treatment.

摘要

源自非乳腺癌肿瘤的乳腺转移极为罕见,仅占所有确诊恶性乳腺肿瘤的0.2 - 1.3%。此外,虽然晚期卵巢癌转移最常见的部位是肝脏、肺和胸膜,但原发性卵巢癌转移至乳腺并不常见,在所有乳腺癌中仅占0.03 - 0.6%。在此,我们报告一例50岁女性患者,罕见地出现晚期卵巢癌乳腺转移,表现为炎性乳腺癌。我们的观察结果强调了在诊断过程中区分原发性和转移性乳腺癌对于恰当预后和治疗的临床重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/da904918165c/CRIOG2016-3476143.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/ee12c2d4178f/CRIOG2016-3476143.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/de352f2e2c3a/CRIOG2016-3476143.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/da904918165c/CRIOG2016-3476143.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/ee12c2d4178f/CRIOG2016-3476143.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/de352f2e2c3a/CRIOG2016-3476143.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63dc/4800108/da904918165c/CRIOG2016-3476143.003.jpg

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本文引用的文献

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PAX8: a sensitive and specific marker to identify cancer cells of ovarian origin for patients prior to neoadjuvant chemotherapy.PAX8:一种用于新辅助化疗前识别卵巢来源癌性细胞的敏感且特异的标志物。
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以炎性乳腺癌表现的转移性卵巢癌:一例报告
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Metastatic breast cancer from gastric and ovarian cancer, mimicking inflammatory breast cancer: report of two cases.源于胃癌和卵巢癌的转移性乳腺癌,酷似炎性乳腺癌:两例报告
Breast Cancer. 2008;15(4):315-20. doi: 10.1007/s12282-008-0040-5. Epub 2008 Mar 1.
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Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary.WT1、CA 125和GCDFP-15的表达作为原发性卵巢癌与卵巢转移性乳腺癌鉴别诊断中的有用标志物。
Am J Surg Pathol. 2005 Nov;29(11):1482-9. doi: 10.1097/01.pas.0000176429.88702.36.
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Serous carcinoma of the ovary and peritoneum with metastases to the breast and axillary lymph nodes: a potential pitfall.卵巢和腹膜浆液性癌伴乳腺及腋窝淋巴结转移:一个潜在的陷阱。
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Cancers metastatic to the breast.转移至乳腺的癌症。
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