Singh A, Randhawa S S, Setia M S
Department of Veterinary Physiology, Punjab Agricultural University, Ludhiana, India.
Res Vet Sci. 1989 Mar;46(2):277-9.
Alterations in acid-base status and blood-gas dynamics were studied during induced progressive hyperkalaemia in neonatal calves. The hyperkalaemia was associated initially with respiratory alkalosis in arterial blood when plasma K+ was increased to 6.08 +/- 1.02 mmol litre-1. The rise of plasma K+ above 6.08 +/- 1.02 mmol litre-1 led to the development of metabolic acidosis in arterial and venous blood. There was partial respiratory compensation. Plasma K+ concentrations at or above 11.03 +/- 0.34 mmol litre-1 were associated with a decrease in arterial oxygen tension and arterial oxygen saturation. The oxygen extraction ratio was increased during hyperkalaemia.
在新生犊牛诱导性进行性高钾血症期间,对酸碱状态和血气动力学变化进行了研究。当血浆钾离子浓度升高至6.08±1.02 mmol/L时,高钾血症最初与动脉血呼吸性碱中毒相关。血浆钾离子浓度升至6.08±1.02 mmol/L以上导致动脉血和静脉血出现代谢性酸中毒。存在部分呼吸代偿。血浆钾离子浓度等于或高于11.03±0.34 mmol/L与动脉血氧分压和动脉血氧饱和度降低相关。高钾血症期间氧摄取率增加。