Setia M S, Singh A, Kahlon R S, Randhawa S S
Department of Veterinary Physiology, College of Veterinary Science, Punjab Agricultural University, Ludhiana, India.
Indian J Exp Biol. 1996 Apr;34(4):375-6.
Hypocalcaemia, induced in cow calves by slow infusion of Na2EDTA for 6 hr, led to biphasic changes in acid-base status. Decrease in ionized plasma Ca2+ concentration upto 0.82 +/- 0.06 mmole 1(-1) was associated with metabolic alkalosis. Further decrease in ionized plasma Ca2+ concentration (0.61 +/- 0.09 mmole 1(-1)) led to metabolic acidosis, superimposed by a respiratory component. There was significant decrease in oxygen tension and saturation of arterial blood as well as impaired uptake of oxygen by peripheral tissues and pulmonary blood.
通过缓慢输注乙二胺四乙酸二钠（Na2EDTA）6小时诱导犊牛出现低钙血症，导致酸碱平衡状态发生双相变化。血浆离子钙浓度降至0.82±0.06毫摩尔/升（-1）与代谢性碱中毒相关。血浆离子钙浓度进一步降低（0.61±0.09毫摩尔/升（-1））导致代谢性酸中毒，并叠加有呼吸成分。动脉血氧张力和饱和度显著降低，外周组织和肺血对氧的摄取也受损。
