2只黑猩猩（黑猩猩属）性皮肤的恶性肿瘤
Malignant Neoplasia of the Sex Skin in 2 Chimpanzees (Pan troglodytes).
作者信息
Beck Amanda P, Magden Elizabeth R, Buchl Stephanie J, Baze Wallace B
机构信息
Michaele E. Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA; Albert Einstein College of Medicine, Bronx, New York, USA.
Michaele E. Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA.
出版信息
Comp Med. 2016 Apr;66(2):154-61.
This report describes 2 cases of spontaneous malignant neoplasia within the sex skin of aged female chimpanzees. In both cases, the initial presentation resembled nonhealing traumatic wounds to the sex skin, with different degrees of infection, ulceration, and tissue necrosis. Histopathology of the lesions confirmed the diagnosis of squamous cell carcinoma in one case and of adenocarcinoma with metastasis in the other. Advanced age and previous trauma likely contributed to the development of the neoplasias in both cases; long-term sun exposure may also have contributed to the development of the squamous cell carcinoma. To our knowledge, these 2 cases represent the first reports of sex skin neoplasia in chimpanzees.
本报告描述了2例老年雌性黑猩猩性皮肤内的自发性恶性肿瘤。在这两个病例中，最初的表现类似于性皮肤的不愈合创伤，伴有不同程度的感染、溃疡和组织坏死。病变的组织病理学检查在一例中确诊为鳞状细胞癌，另一例为伴有转移的腺癌。高龄和既往创伤可能在这两个病例中都促成了肿瘤的发生；长期日晒也可能促成了鳞状细胞癌的发生。据我们所知，这2例代表了黑猩猩性皮肤肿瘤的首次报道。
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