Zhou Zhixiong, Xi Yubao, Zhang Fan, Lu Qing, Zhang Fubing, Huang Dechun, Ren Hong, Wang Kaizhen, Yin Zenong
Capital University of Physical Education and Sports, Beijing (Dr Zhou, Zhang, Lu, Dr Wang); College of Sports Science, Anhui Normal University, Wuhu (Xi, Huang); Health Center, Beijing University of Civil Engineering and Architecture (Zhang); School of Sport Sciences, Beijing Sport University, China (Dr Ren); and Department of Kinesiology, Health and Nutrition, the University of Texas at San Antonio (Dr Yin).
J Occup Environ Med. 2016 Apr;58(4):e117-23. doi: 10.1097/JOM.0000000000000673.
The purpose of the study was to examine the longitudinal influence of sedentary behavior on the development of metabolic syndrome (MS) and cardiometabolic risk in professional workers.
Study participants were 203 professional workers (55.6% female; mean age = 41.9, SD = 11.2,) in low physical activity occupations. Participants' height, weight, waist circumference, fasting plasma glucose, triglycerides, high-density lipoprotein, total cholesterol, and low-density lipoprotein were measured at the baseline and follow-up over 12 months. Accelerometry was used to assess the sedentary time and moderate and vigorous physical activity.
High level of sedentary behavior at baseline significantly predicted incident MS (odds ratio 4.07, 95% confidence interval 1.69 to 9.76) at follow-up. Similarly, the change in sedentary behavior significantly predicted the change in the cardiometabolic risk score (B = 0.12, SE = 0.06, P = 0.03) from baseline to the follow-up.
Professional workers in low physical activity occupations were engaged in an excessive amount of sedentary behavior that predisposed them to an increased risk of developing cardiometabolic disorders.
本研究旨在探讨久坐行为对职业工作者代谢综合征（MS）发展及心脏代谢风险的纵向影响。
研究参与者为203名从事低体力活动职业的职业工作者（女性占55.6%；平均年龄 = 41.9岁，标准差 = 11.2）。在基线和12个月的随访期间测量参与者的身高、体重、腰围、空腹血糖、甘油三酯、高密度脂蛋白、总胆固醇和低密度脂蛋白。使用加速度计评估久坐时间以及中度和剧烈体力活动。
基线时的高水平久坐行为显著预测了随访时发生的MS（比值比4.07，95%置信区间1.69至9.76）。同样，久坐行为的变化显著预测了从基线到随访期间心脏代谢风险评分的变化（B = 0.12，标准误 = 0.06，P = 0.03）。
从事低体力活动职业的职业工作者久坐行为过多，这使他们患心脏代谢疾病的风险增加。
