Gurovich Isaac Ya, Papsuev Oleg O, Shmukler Alexander B, Movina Larisa G, Storozhakova Yanina A, Kiryanova Elena M
Department of Outpatient Psychiatry and Organization of Psychiatric Care, Moscow Research Institute of Psychiatry, Moscow, Russia.
Psych J. 2016 Mar;5(1):36-47. doi: 10.1002/pchj.126.
Neurocognition and social cognition are the core deficits influencing social outcomes in patients with schizophrenia. These deficits are present in the prodromal phase, throughout the illness and in first-degree relatives. They are considered in the framework of neurodevelopmental or neurodegenerative models as well as candidates for endophenotypes of schizophrenia. Four clinical cases with patients reflecting different cognitive profiles were chosen to demonstrate heterogeneity of cognitive biases and their influence on social function in vivo. The patients had undergone a number of neurocognitive and social cognitive measures. Better functioning was observed in patients with less affected domains of emotional processing and theory of mind, while neurocognitive statuses were incongruent to levels of social functioning. Further investigation on large samples concerning capacity for empathy and its role in social functioning is needed.
神经认知和社会认知是影响精神分裂症患者社会结局的核心缺陷。这些缺陷在疾病前驱期、整个病程中以及一级亲属中均存在。它们在神经发育或神经退行性模型框架内被加以考量，同时也是精神分裂症内表型的候选因素。选取了4例具有不同认知特征的患者的临床病例，以证明认知偏差的异质性及其对实际社会功能的影响。这些患者接受了多项神经认知和社会认知测量。在情感加工和心理理论受影响较小的领域中，患者的功能表现更好，而神经认知状态与社会功能水平并不一致。需要对同理心能力及其在社会功能中的作用进行更大样本的进一步研究。
