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定坤丹临床应用的系统评价

[Systematic evaluation of clinical application of Dingkun Dan].

作者信息

Chen Yan-xia, Ma Kun

出版信息

Zhongguo Zhong Yao Za Zhi. 2015 Oct;40(20):3916-9.

PMID:27062801
Abstract

Dingkun Dan is a representative of the classic gynecological medicine. With Tonifying the liver and kidney, supplementing Qi and nourishing blood, regulating menstruation Shuyu, promoting the role of pain. Used in treatment of liver and kidney deficiency, deficiency of both qi and blood, Qi stagnation and blood stasis caused by irregular menstruation, menstrual pain, uterine bleeding, leukorrhea with reddish discharge, bruise blood removal, infertility, and various postpartum deficiency and bone steaming hot flashes of gynecological common disease. In recent years, Dingkun Dan's new uses have been reported, the clinical application value is worth further digging. In this paper, clinical application and research progress of Dingkun Dan since the founding of new China were briefly discussed, and summarize for the randomized controlled trials.

摘要

定坤丹是经典妇科用药的代表。具有滋补肝肾、益气养血、调经舒郁、止痛之功效。用于治疗肝肾不足、气血两虚、气滞血瘀所致的月经不调、行经腹痛、崩漏下血、赤白带下、瘀血内停、不孕不育以及各种妇科常见病的产后诸虚、骨蒸潮热。近年来,定坤丹有新用途的报道,其临床应用价值值得进一步挖掘。本文简述新中国成立以来定坤丹的临床应用及研究进展,并对随机对照试验进行总结。

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1
[Systematic evaluation of clinical application of Dingkun Dan].定坤丹临床应用的系统评价
Zhongguo Zhong Yao Za Zhi. 2015 Oct;40(20):3916-9.
2
[Impact of prostaglandin F2α and endothelin, pulsation index and resistance index of uterine artery blood flow on dysmenorrhea patients of cold stagnation and blood stasis syndrome with Dingkun Dan].[前列腺素F2α、内皮素、子宫动脉血流搏动指数及阻力指数对痛经寒凝血瘀证患者应用定坤丹的影响]
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Strategies for Activating Blood Circulation-Regulating Gan (Liver)-Tonifying Shen (Kidney) Sequential Therapy of Endometriosis-Associated Infertility.活血化瘀-调补肝肾序贯疗法治疗子宫内膜异位症相关不孕策略。
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引用本文的文献

1
The Efficacy and Safety of Dingkun Pill in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.定坤丹治疗多囊卵巢综合征女性的疗效与安全性:一项随机对照试验的系统评价和Meta分析
Evid Based Complement Alternat Med. 2022 Aug 24;2022:8698755. doi: 10.1155/2022/8698755. eCollection 2022.
2
The Role of Traditional Chinese Formula Ding-Kun Pill (DKP) in Expected Poor Ovarian Response Women (POSEIDON Group 4) Undergoing Fertilization-Embryo Transfer: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.定坤丹对卵巢低反应患者体外受精-胚胎移植结局的影响:多中心、随机、双盲、安慰剂对照临床研究。
Front Endocrinol (Lausanne). 2021 Jun 17;12:675997. doi: 10.3389/fendo.2021.675997. eCollection 2021.
3
Efficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization/intracytoplasmic sperm injection: study protocol for a randomized controlled trial.定坤丹用于体外受精/卵胞浆内单精子注射治疗中预测卵巢反应不良的女性不孕症患者的疗效与安全性:一项随机对照试验的研究方案
Trials. 2018 Feb 20;19(1):124. doi: 10.1186/s13063-018-2511-0.