Lin Wan-fu, Wang Chen, Ling Chang-quan
Zhongguo Zhong Yao Za Zhi. 2015 Oct;40(20):3937-40.
Emodin is one of the main active ingredient of Rheum palmatum, and has anti-inflammatory, anti-bacterial, anti-viral and other effects. In recent years, it arouse concern since it has a significant anti-tumor effect with low toxicity. In this paper we mainly report the anti-cancer effects of emodin according to the studies of the past five years, including four parts such as inhibit tumor growth, inhibit migration and invasion, enhance the efficacy of combination therapy, increase chemosensitivity and attenuated side effects. We hope that our work may provide a reference for further study.
大黄素是掌叶大黄的主要活性成分之一,具有抗炎、抗菌、抗病毒等作用。近年来,因其具有显著的抗肿瘤作用且毒性低而受到关注。本文主要根据过去五年的研究报道大黄素的抗癌作用,包括抑制肿瘤生长、抑制迁移和侵袭、增强联合治疗疗效、增加化疗敏感性和减轻副作用等四个方面。希望我们的工作可为进一步研究提供参考。