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一种水溶性钆金属富勒醇:简便制备、磁性及磁共振成像应用

A water-soluble gadolinium metallofullerenol: facile preparation, magnetic properties and magnetic resonance imaging application.

作者信息

Li Jie, Wang Taishan, Feng Yongqiang, Zhang Ying, Zhen Mingming, Shu Chunying, Jiang Li, Wang Yuqing, Wang Chunru

机构信息

Beijing National Laboratory for Molecular Sciences, Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

出版信息

Dalton Trans. 2016 Jun 7;45(21):8696-9. doi: 10.1039/c6dt00223d. Epub 2016 Apr 11.

DOI:10.1039/c6dt00223d
PMID:27064096
Abstract

A new water-soluble gadolinium metallofullerenol was prepared through a solid-liquid reaction. It was characterized to have an enhanced effective magnetic moment, and improved T1-weighted relaxivity and magnetic resonance imaging performance in the liver. This material prepared by a facile method has wide application as a contrast agent and biological medicine.

摘要

通过固液反应制备了一种新型水溶性钆金属富勒醇。经表征,其有效磁矩增强,在肝脏中的 T1 加权弛豫率和磁共振成像性能得到改善。这种通过简便方法制备的材料作为造影剂和生物药物具有广泛的应用。

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