Coslett H B, Saffran E M
Department of Neurology, Temple University Hospital, Philadelphia, PA 19140.
Brain. 1989 Apr;112 ( Pt 2):327-59. doi: 10.1093/brain/112.2.327.
We describe 4 patients who developed pure alexia after infarctions of the left cerebral hemisphere. All subjects employed a letter-by-letter strategy (with varying degrees of success) to explicitly identify visually presented words. Although all 4 subjects explicitly denied that they could identify briefly presented words, they all performed significantly better than chance on lexical decision and forced-choice semantic categorization tasks with briefly presented words which they could not explicitly identify. Three subjects regained the ability to explicitly identify briefly presented words; these subjects were more accurate with nouns than functors and words of high as compared with low imageability. Additionally, these subjects were impaired in the processing of suffixes. These data are not accommodated by the 'disconnection' account of pure alexia but are more consistent with the hypothesis that reading in these patients is mediated by the right hemisphere.
我们描述了4例在左侧大脑半球梗死之后出现纯失读症的患者。所有受试者都采用逐个字母的策略（成功程度各异）来明确识别视觉呈现的单词。尽管所有4名受试者都明确否认自己能够识别短暂呈现的单词，但在对他们无法明确识别的短暂呈现单词进行词汇判断和强制选择语义分类任务时，他们的表现均显著优于随机水平。3名受试者恢复了明确识别短暂呈现单词的能力；与功能词相比，这些受试者对名词的识别更准确，与低意象性单词相比，对高意象性单词的识别更准确。此外，这些受试者在后缀处理方面存在障碍。纯失读症的“分离”理论无法解释这些数据，而这些数据更符合以下假设：这些患者的阅读是由右脑介导的。
