Yoo Ha Yeong, Kim Mock Ryeon, Park Hye Won, Son Jae Sung, Bae Sun Hwan
Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.
Pediatr Gastroenterol Hepatol Nutr. 2016 Mar;19(1):38-43. doi: 10.5223/pghn.2016.19.1.38. Epub 2016 Mar 22.
Each ethnic group has a unique life style, including diets. Life style affects bowel movement. The aim of this study is to describe the results of colon transit time (CTT) tests in Korean children who had chronic functional constipation based on highly refined data.
One hundred ninety (86 males) out of 415 children who performed a CTT test under the diagnosis of chronic constipation according to Rome III criteria at Konkuk University Medical Center from January 2006 through March 2015 were enrolled in this study. Two hundreds twenty-five children were excluded on the basis of CTT test result, defecation diary, and clinical setting. Shapiro-Wilk and Mann-Whitney U, and chi-square tests were used for statistical analysis.
The median value and interquartile range (IQR) of CTT was 54 (37.5) hours in Encopresis group, and those in non-encopresis group was 40.2 (27.9) hours (p<0.001). The frequency of subtype between non-encopresis group and encopresis was statistically significant (p=0.002). The non-encopresis group (n=154, 81.1%) was divided into normal transit subgroup (n=84, 54.5%; median value and IQR of CTT=26.4 [9.6] hours), outlet obstruction subgroup (n=18, 11.7%; 62.4 [15.6] hours), and slow transit subgroup (n=52, 33.8%; 54.6 [21.0] hours]. The encopresis group (n=36, 18.9%) was divided into normal transit subgroup (n=8, 22.2%; median value and IQR of CTT=32.4 [9.9] hours), outlet obstruction subgroup (n=8, 22.2%; 67.8 [34.8] hours), and slow transit subgroup (n=20, 55.6%; 59.4 [62.7]hours).
This study provided the basic pattern and value of the CTT test in Korean children with chronic constipation.
每个种族都有独特的生活方式，包括饮食。生活方式会影响排便。本研究的目的是基于高度精确的数据描述韩国慢性功能性便秘儿童的结肠传输时间（CTT）测试结果。
2006年1月至2015年3月在建国大学医学中心根据罗马III标准诊断为慢性便秘并进行CTT测试的415名儿童中，有190名（86名男性）纳入本研究。根据CTT测试结果、排便日记和临床情况排除了225名儿童。采用Shapiro-Wilk检验、Mann-Whitney U检验和卡方检验进行统计分析。
大便失禁组CTT的中位数和四分位数间距（IQR）为54（37.5）小时，非大便失禁组为40.2（27.9）小时（p<0.001）。非大便失禁组和大便失禁组之间的亚型频率具有统计学意义（p=0.002）。非大便失禁组（n=154，81.1%）分为正常传输亚组（n=84，54.5%；CTT的中位数和IQR=26.4[9.6]小时）、出口梗阻亚组（n=18，11.7%；62.4[15.6]小时）和慢传输亚组（n=52，33.8%；54.6[21.0]小时）。大便失禁组（n=36，18.9%）分为正常传输亚组（n=8，22.2%；CTT的中位数和IQR=32.4[9.9]小时）、出口梗阻亚组（n=8，22.2%；67.8[34.8]小时）和慢传输亚组（n=20，55.6%；59.4[62.7]小时）。
本研究提供了韩国慢性便秘儿童CTT测试的基本模式和数值。
