便秘的预后：临床因素与结肠运输时间
Prognosis of constipation: clinical factors and colonic transit time.
作者信息
de Lorijn F, van Wijk M P, Reitsma J B, van Ginkel R, Taminiau J A J M, Benninga M A
机构信息
Department of Paediatric Gastroenterology and Nutrition, Emma Children's Hospital/Academic Medical Centre, Amsterdam, Netherlands.
出版信息
Arch Dis Child. 2004 Aug;89(8):723-7. doi: 10.1136/adc.2003.040220.
BACKGROUND
Measurement of colonic transit time (CTT) is sometimes used in the evaluation of patients with chronic constipation.
AIM
To investigate the relation between symptoms and CTT, and to assess the importance of symptoms and CTT in predicting outcome.
METHODS
Between 1995 and 2000, 169 consecutive patients (median age 8.4 years, 65% boys) fulfilling the criteria for constipation were enrolled. During the intervention and follow up period, all kept a diary to record symptoms. CTT was measured at entry to the study.
RESULTS
At entry, defecation frequency was lower in girls than in boys, while the frequency of encopresis episodes was higher in boys. CTT values were significantly higher in those with a low defecation frequency (< or =1/week) and a high frequency of encopresis (> or =2/day). However, 50% had CTT values within the normal range. Successful outcome occurred more often in those with a rectal impaction. CTT results <100 hours were not predictive of outcome. However, those with CTT >100 hours were less likely to have had a successful outcome.
CONCLUSION
The presence of a rectal impaction at presentation is associated with a better outcome at one year. A CTT >100 hours is associated with a poor outcome at one year.
背景
结肠传输时间（CTT）的测量有时用于慢性便秘患者的评估。
目的
研究症状与CTT之间的关系，并评估症状和CTT在预测预后方面的重要性。
方法
在1995年至2000年期间，连续纳入169例符合便秘标准的患者（中位年龄8.4岁，65%为男孩）。在干预和随访期间，所有患者都记日记记录症状。在研究开始时测量CTT。
结果
在研究开始时，女孩的排便频率低于男孩，而男孩的大便失禁发作频率更高。排便频率低（≤1/周）和大便失禁频率高（≥2/天）的患者CTT值显著更高。然而，50%的患者CTT值在正常范围内。直肠嵌塞患者的预后更常成功。CTT结果<100小时不能预测预后。然而，CTT>100小时的患者成功预后的可能性较小。
结论
就诊时存在直肠嵌塞与一年后的较好预后相关。CTT>100小时与一年后的不良预后相关。
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