Smitha S G, Jagannath B, Mathew Amrita Suzanne
Department of ENT, Kempegowda Institute of Medical Sciences, K.R Road, V.V Puram, Bangalore, 560004 Karnataka India.
Indian J Otolaryngol Head Neck Surg. 2016 Mar;68(1):46-51. doi: 10.1007/s12070-015-0840-9. Epub 2015 Feb 17.
This study aims to evaluate the effect of septal correction on the blood pressure (BP) of patients with symptomatic nasal septal deviation and to assess whether a positive association exists between deviated nasal septum and hypertension. A prospective observational clinical study was conducted at Kempegowda Institute of Medical Sciences, Bangalore. Hundred adults, aged 18-40 years, with symptomatic nasal septal deviation, newly detected untreated hypertension (mean BP ≥140/90 mmHg), undergoing submucosal resection of the septum and submucosal diathermy of hypertrophied inferior turbinate (when present), were included. Postoperative follow up for ENT examination and BP measurement was done at 1, 6 and 12 months. Seventy five males and 25 females met the inclusion criteria. 48 % were aged 31-35 years (mean = 31.83 ± 5.19 years). 71 % had anterior septal deviation, 13 % posterior deviation and 16 % a combination of both. Preoperatively, mean systolic blood pressure was 141.82 ± 1.70 mmHg and mean diastolic blood pressure was 91.04 ± 1.21 mmHg, which postoperatively decreased by 10-12 mmHg and 4-5 mmHg respectively. 79 % showed a significant (P < 0.001) decrease in BP postoperatively. 13 % showed no change in BP, of which 53.8 % had posterior deviation, demonstrating a significant association (P < 0.001) between type of deviation and response to surgery. In 8 %, a rise in BP over the follow up period was seen; of these, 62.5 % were aged 36-40 years, indicating a significant association (P < 0.001) between age and BP. Surgical correction of septal deviation is thus effective in controlling the BP of patients with anterior deviation, aged <35 years.
本研究旨在评估鼻中隔矫正对有症状的鼻中隔偏曲患者血压(BP)的影响,并评估鼻中隔偏曲与高血压之间是否存在正相关。在班加罗尔的 Kempegowda 医学科学研究所进行了一项前瞻性观察性临床研究。纳入了 100 名年龄在 18 - 40 岁之间、有症状的鼻中隔偏曲、新检测出未经治疗的高血压(平均血压≥140/90 mmHg)、正在接受鼻中隔黏膜下切除术和(如有)下鼻甲肥大黏膜下透热疗法的成年人。术后在 1、6 和 12 个月进行耳鼻喉检查和血压测量的随访。75 名男性和 25 名女性符合纳入标准。48%的患者年龄在 31 - 35 岁之间(平均 = 31.83 ± 5.19 岁)。71%有前鼻中隔偏曲,13%有后鼻中隔偏曲,16%两者皆有。术前,平均收缩压为 141.82 ± 1.70 mmHg,平均舒张压为 91.04 ± 1.21 mmHg,术后分别下降了 10 - 12 mmHg 和 4 - 5 mmHg。79%的患者术后血压显著(P < 0.001)下降。13%的患者血压无变化,其中 53.8%有后鼻中隔偏曲,表明偏曲类型与手术反应之间存在显著关联(P < 0.001)。在 8%的患者中,随访期间血压升高;其中,62.5%的患者年龄在 36 - 40 岁之间,表明年龄与血压之间存在显著关联(P < 0.001)。因此,鼻中隔偏曲的手术矫正对于控制年龄 < 35 岁的前鼻中隔偏曲患者的血压是有效的。