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本文引用的文献

1
Pulmonary artery pressure in patients with markedly deviated septum candidate for septorhinoplasty.鼻中隔明显偏曲且拟行鼻中隔成形术患者的肺动脉压
World J Plast Surg. 2014 Jul;3(2):119-21.
2
Measurement tools for the diagnosis of nasal septal deviation: a systematic review.鼻中隔偏曲诊断的测量工具:系统评价。
J Otolaryngol Head Neck Surg. 2014 Apr 24;43(1):11. doi: 10.1186/1916-0216-43-11.
3
Socio-demographic inequalities in the prevalence, diagnosis and management of hypertension in India: analysis of nationally-representative survey data.印度高血压患病率、诊断和管理方面的社会人口统计学不平等:基于全国代表性调查数据的分析
PLoS One. 2014 Jan 23;9(1):e86043. doi: 10.1371/journal.pone.0086043. eCollection 2014.
4
Nasal septoplasty with submucosal diathermy to inferior turbinates improves symptoms at 3 months postoperatively in a study of one hundred and one patients.在一项针对101名患者的研究中,鼻中隔成形术联合下鼻甲黏膜下透热疗法在术后3个月可改善症状。
Clin Otolaryngol. 2014 Feb;39(1):57-63. doi: 10.1111/coa.12219.
5
Correlation of nasal obstruction with nasal cross-sectional area measured by computed tomography in patients with nasal septal deviation.鼻中隔偏曲患者鼻阻塞与计算机断层扫描测量的鼻腔横截面积的相关性
Ann Otol Rhinol Laryngol. 2012 Apr;121(4):239-45. doi: 10.1177/000348941212100409.
6
Septal deviation and nasal resistance: an investigation using virtual surgery and computational fluid dynamics.中隔偏曲和鼻腔阻力:应用虚拟手术和计算流体动力学的研究。
Am J Rhinol Allergy. 2010 Jan-Feb;24(1):e46-53. doi: 10.2500/ajra.2010.24.3428.
7
Parasympathetic overactivity in patients with nasal septum deformities.鼻中隔畸形患者的副交感神经活动过度。
Eur Arch Otorhinolaryngol. 2010 Jan;267(1):73-6. doi: 10.1007/s00405-009-1055-z.
8
Nasal resistance for determinant factor of nasal surgery in CPAP failure patients with obstructive sleep apnea syndrome.鼻阻力是阻塞性睡眠呼吸暂停综合征持续气道正压通气治疗失败患者鼻腔手术的决定因素。
Rhinology. 2005 Dec;43(4):296-9.
9
Expanding the definition and classification of hypertension.拓展高血压的定义与分类
J Clin Hypertens (Greenwich). 2005 Sep;7(9):505-12. doi: 10.1111/j.1524-6175.2005.04769.x.
10
The effect of carbon dioxide, respiratory rate and tidal volume on human heart rate variability.二氧化碳、呼吸频率和潮气量对人体心率变异性的影响。
Acta Anaesthesiol Scand. 2004 Jan;48(1):93-101. doi: 10.1111/j.1399-6576.2004.00272.x.

鼻中隔矫正对鼻中隔偏曲高血压患者血压的影响。

Impact of Septal Correction on the Blood Pressure of Hypertensive Patients with Deviated Nasal Septum.

作者信息

Smitha S G, Jagannath B, Mathew Amrita Suzanne

机构信息

Department of ENT, Kempegowda Institute of Medical Sciences, K.R Road, V.V Puram, Bangalore, 560004 Karnataka India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2016 Mar;68(1):46-51. doi: 10.1007/s12070-015-0840-9. Epub 2015 Feb 17.

DOI:10.1007/s12070-015-0840-9
PMID:27066410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4809816/
Abstract

This study aims to evaluate the effect of septal correction on the blood pressure (BP) of patients with symptomatic nasal septal deviation and to assess whether a positive association exists between deviated nasal septum and hypertension. A prospective observational clinical study was conducted at Kempegowda Institute of Medical Sciences, Bangalore. Hundred adults, aged 18-40 years, with symptomatic nasal septal deviation, newly detected untreated hypertension (mean BP ≥140/90 mmHg), undergoing submucosal resection of the septum and submucosal diathermy of hypertrophied inferior turbinate (when present), were included. Postoperative follow up for ENT examination and BP measurement was done at 1, 6 and 12 months. Seventy five males and 25 females met the inclusion criteria. 48 % were aged 31-35 years (mean = 31.83 ± 5.19 years). 71 % had anterior septal deviation, 13 % posterior deviation and 16 % a combination of both. Preoperatively, mean systolic blood pressure was 141.82 ± 1.70 mmHg and mean diastolic blood pressure was 91.04 ± 1.21 mmHg, which postoperatively decreased by 10-12 mmHg and 4-5 mmHg respectively. 79 % showed a significant (P < 0.001) decrease in BP postoperatively. 13 % showed no change in BP, of which 53.8 % had posterior deviation, demonstrating a significant association (P < 0.001) between type of deviation and response to surgery. In 8 %, a rise in BP over the follow up period was seen; of these, 62.5 % were aged 36-40 years, indicating a significant association (P < 0.001) between age and BP. Surgical correction of septal deviation is thus effective in controlling the BP of patients with anterior deviation, aged <35 years.

摘要

本研究旨在评估鼻中隔矫正对有症状的鼻中隔偏曲患者血压(BP)的影响,并评估鼻中隔偏曲与高血压之间是否存在正相关。在班加罗尔的 Kempegowda 医学科学研究所进行了一项前瞻性观察性临床研究。纳入了 100 名年龄在 18 - 40 岁之间、有症状的鼻中隔偏曲、新检测出未经治疗的高血压(平均血压≥140/90 mmHg)、正在接受鼻中隔黏膜下切除术和(如有)下鼻甲肥大黏膜下透热疗法的成年人。术后在 1、6 和 12 个月进行耳鼻喉检查和血压测量的随访。75 名男性和 25 名女性符合纳入标准。48%的患者年龄在 31 - 35 岁之间(平均 = 31.83 ± 5.19 岁)。71%有前鼻中隔偏曲,13%有后鼻中隔偏曲,16%两者皆有。术前,平均收缩压为 141.82 ± 1.70 mmHg,平均舒张压为 91.04 ± 1.21 mmHg,术后分别下降了 10 - 12 mmHg 和 4 - 5 mmHg。79%的患者术后血压显著(P < 0.001)下降。13%的患者血压无变化,其中 53.8%有后鼻中隔偏曲,表明偏曲类型与手术反应之间存在显著关联(P < 0.001)。在 8%的患者中,随访期间血压升高;其中,62.5%的患者年龄在 36 - 40 岁之间,表明年龄与血压之间存在显著关联(P < 0.001)。因此,鼻中隔偏曲的手术矫正对于控制年龄 < 35 岁的前鼻中隔偏曲患者的血压是有效的。