Lee Dong Hoon, Yoon Tae Mi, Kim Hee Kyung, Lee Joon Kyoo, Kang Ho Cheol, Lim Sang Chul
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam 519-809 South Korea.
Department of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Jeonnam South Korea.
Indian J Otolaryngol Head Neck Surg. 2016 Mar;68(1):56-9. doi: 10.1007/s12070-015-0900-1. Epub 2015 Sep 15.
The purpose of this study was to evaluate the usefulness and accuracy of intraoperative frozen section examination in the diagnosis of metastatic central lymph nodes in comparison to the final histopathological findings. A retrospective review was performed to evaluate patients with a preoperative diagnosis of papillary thyroid microcarcinoma (PTMC) and a plan to perform thyroid lobectomy at our Hospital from September 2011 to September 2013. Sixteen patients were identified. Intraoperative frozen section examination diagnosed ten patients as negative malignant cells of the central lymph node and the remaining six patients as metastatic central lymph node. The final histopathological results corresponded with intraoperative frozen section examination. Intraoperative frozen section examination had a sensitivity, specificity and accuracy of 100 % for diagnosing metastatic central lymph nodes of PTMC. Intraoperative frozen section examination of central lymph nodes is a useful and accurate adjunct for determining the operation method in PTMC.
本研究的目的是评估术中冰冻切片检查在诊断转移性中央淋巴结方面的实用性和准确性，并与最终的组织病理学结果进行比较。对2011年9月至2013年9月在我院术前诊断为甲状腺微小乳头状癌（PTMC）且计划行甲状腺叶切除术的患者进行回顾性研究。共纳入16例患者。术中冰冻切片检查诊断出10例患者中央淋巴结恶性细胞为阴性，其余6例患者为转移性中央淋巴结。最终组织病理学结果与术中冰冻切片检查结果相符。术中冰冻切片检查诊断PTMC转移性中央淋巴结的敏感性、特异性和准确性均为100%。术中对中央淋巴结进行冰冻切片检查是确定PTMC手术方式的一种有用且准确的辅助手段。
