Cheaha Dania, Issuriya Acharaporn, Manor Rodiya, Kwangjai Jackapun, Rujiralai Thitima, Kumarnsit Ekkasit
Faculty of Medicine, Princess of Naradhiwas University, Khok Khian, Muang, Narathiwat, 96000, Thailand.
Faculty of Veterinary Science (The Establishment Project), Prince of Songkla University, Songkhla 90110, Thailand.
J Intercult Ethnopharmacol. 2016 Feb 14;5(1):72-8. doi: 10.5455/jice.20160208050736. eCollection 2016 Jan-Feb.
Essential oils (EOs) have been claimed to modulate mental functions though the most of data were obtained from subjective methods of assessment. Direct effects of EO on brain function remained largely to be confirmed with scientific proof. This study aimed to demonstrate quantifiable and reproducible effects of commercial vetiver (Vetiveria zizanioides) EO inhalation on sleep-waking and electroencephalogram (EEG) patterns in adult male Wistar rats. The experiments were conducted during November 2013 - February 2014.
The following electrode implantation on the skull, control, and treated animals were subjected for EEG recording while inhaling water and vetiver EO (20 and 200 µl), respectively. Fast Fourier transform was used for analysis of EEG power spectrum.
One-way ANOVA analysis confirmed that vetiver EO inhalation significantly increased total waking and reduced slow-wave sleep time. Moreover, EO inhalation decreased alpha and beta1 activity in both frontal and parietal cortices and increased gamma activity in the frontal cortex. Changes in these frequencies began almost from the start of the inhalation.
These data suggest refreshing properties of vetiver EO on electrical brain activity and alertness.
尽管大多数数据是通过主观评估方法获得的，但精油（EOs）被认为可调节心理功能。EO对脑功能的直接影响在很大程度上仍有待科学证据证实。本研究旨在证明成年雄性Wistar大鼠吸入市售香根草（Vetiveria zizanioides）EO对睡眠 - 觉醒和脑电图（EEG）模式具有可量化和可重复的影响。实验于2013年11月至2014年2月进行。
在颅骨上进行以下电极植入，对对照组和处理组动物分别在吸入水和香根草EO（20和200微升）时进行EEG记录。采用快速傅里叶变换分析EEG功率谱。
单因素方差分析证实，吸入香根草EO可显著增加总觉醒时间并减少慢波睡眠时间。此外，吸入EO可降低额叶和顶叶皮质的α和β1活动，并增加额叶皮质的γ活动。这些频率的变化几乎从吸入开始就出现。
这些数据表明香根草EO对脑电活动和警觉性具有提神作用。
