Varney N R, Damasio H, Adler S
Psychology Service, VA Medical Center, Iowa City, IA 52240.
Cortex. 1989 Mar;25(1):47-55. doi: 10.1016/s0010-9452(89)80005-x.
This study was concerned with the relationship between locus of lesion and subtypes of language comprehension defect in aphasia. Previous studies had indicated that performance in sound recognition identified two subtypes of aural comprehension deficit and that performance in pantomime recognition identified two subtypes of reading comprehension defect. Defects in sound recognition and pantomime recognition were found in association with a variety of lesion loci. However, comprehension defective aphasics with normal sound recognition or pantomime recognition had lesions closely similar in location and size to those of aphasics who performed poorly on these tests. Findings suggest that whether an aphasic with a language comprehension defect is impaired in sound recognition or pantomime recognition depends, at least in part, on individually variable predisposing factors. It would appear possible that this phenomenon reflects a separate dimension of hemispheric cerebral dominance.
本研究关注失语症患者的损伤部位与语言理解缺陷亚型之间的关系。先前的研究表明，声音识别表现可确定听觉理解缺陷的两种亚型，而手势识别表现可确定阅读理解缺陷的两种亚型。声音识别和手势识别缺陷与多种损伤部位相关。然而，声音识别或手势识别正常但存在理解缺陷的失语症患者，其损伤部位在位置和大小上与在这些测试中表现较差的失语症患者的损伤部位极为相似。研究结果表明，语言理解存在缺陷的失语症患者在声音识别或手势识别方面是否受损，至少部分取决于个体可变的 predisposing 因素。这种现象似乎有可能反映了大脑半球优势的一个独立维度。 （注：predisposing 这个词在医学语境中可能不太常见，推测可能是“ predisposing factor”（易患因素）的错误表述，按原文翻译了）
