Lin Shih-Chieh, Sun Chien-An, You San-Lin, Hwang Lee-Ching, Liang Chun-Yu, Yang Tsan, Bai Chyi-Huey, Chen Chien-Hua, Wei Cheng-Yu, Chou Yu-Ching
Graduate Institute of Life Sciences, National Defense Medical Center, Taipei City, Taiwan.
Department of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
Sleep. 2016 Jun 1;39(6):1261-6. doi: 10.5665/sleep.5848.
The aims of this study are to investigate the relationships of metabolic syndrome (MetS) with insomnia symptoms and sleep duration in a Chinese adult population.
Data from a nationwide epidemiological survey conducted on residents from randomly selected districts in Taiwan in 2007 were used for this cross-sectional population-based study. A total of 4,197 participants were included in this study. Insomnia symptoms, including difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS), early morning awakening (EMA), were assessed using the Insomnia Self-Assessment Inventory questionnaire. Subjects were divided into 3 groups based upon their reported sleep duration (< 7, 7-8, and ≥ 9 h per night). Odds ratios (ORs) and 95% confidence intervals (CIs) derived from multivariable logistic regression were used to evaluate the study aims.
The endorsement of DIS and DMS were cross-sectionally associated with the MetS after adjustment for sleep duration (OR [95% CI] was 1.24 [1.01-1.51] and 1.28 [1.02-1.61], respectively). In addition, short sleep duration was significantly associated with the prevalence of MetS independent of insomnia symptoms (OR [95% CI] was 1.54 [1.05-2.47]). However, there was no significant combined effect of insomnia symptoms and sleep duration on the prevalence of MetS.
The current investigation shows that short sleep duration and insomnia symptoms, specifically DIS and DMS, were significant correlates of MetS. These findings should be replicated in prospective studies using both sleep duration and sleep quality measures.
本研究旨在探讨中国成年人群中代谢综合征（MetS）与失眠症状及睡眠时间的关系。
本横断面人群研究使用了2007年对台湾随机选取地区居民进行的全国性流行病学调查数据。本研究共纳入4197名参与者。使用失眠自评量表问卷评估失眠症状，包括入睡困难（DIS）、睡眠维持困难（DMS）、早醒（EMA）。根据报告的睡眠时间（每晚<7、7 - 8和≥9小时）将受试者分为3组。采用多变量逻辑回归得出的比值比（OR）和95%置信区间（CI）来评估研究目的。
在调整睡眠时间后，DIS和DMS的认可与MetS存在横断面关联（OR [95% CI]分别为1.24 [1.01 - 1.51]和1.28 [1.02 - 1.61]）。此外，睡眠时间短与MetS的患病率显著相关，且独立于失眠症状（OR [95% CI]为1.54 [1.05 - 2.47]）。然而，失眠症状和睡眠时间对MetS患病率没有显著的联合效应。
当前调查表明，睡眠时间短和失眠症状，特别是DIS和DMS，是MetS的显著相关因素。这些发现应在前瞻性研究中使用睡眠时间和睡眠质量测量方法进行重复验证。
