睡眠时间短与代谢综合征在貌似健康人群中的高发率相关。

Short sleep duration associated with a higher prevalence of metabolic syndrome in an apparently healthy population.

机构信息

Department of Family Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan, 70403, Taiwan, ROC.

Department of Family Medicine, National Cheng Kung University Hospital, 138, Sheng Li Road, Tainan, 70403, Taiwan, ROC; Department of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138, Sheng Li Road, Tainan, 70403, Taiwan, ROC.

出版信息

Prev Med. 2012 Oct;55(4):305-309. doi: 10.1016/j.ypmed.2012.07.013. Epub 2012 Jul 27.

DOI:10.1016/j.ypmed.2012.07.013

PMID:22846501

Abstract

OBJECTIVE

To examine the association between sleep duration and metabolic syndrome in an apparently healthy Chinese population.

METHOD

The baseline data were collected from a health examination center in Tainan, Taiwan, from October 1, 2006, to August 31, 2009. A total of 7100 adults were recruited. Subjects were classified into three groups according to their sleep duration: short (<6 h), normal (6-8 h), and long sleepers (>8 h).

RESULTS

There were significant differences in age, gender, education level, fasting plasma glucose, and the proportion of smoking status and exercise frequency among different sleep groups. Based on multiple logistic regression, short sleepers were positively associated with metabolic syndrome (OR=1.28, 95% CI: 1.01-1.63) in males but not in females (OR=1.04, 95% CI: 0.72-1.51). Long sleepers were not related with metabolic syndrome in both genders. Short sleep duration was independently related to hyperglycemia (OR=1.39, 95% CI: 1.10-1.74) also in males only. Other components such as hypertriglyceridemia, low high density lipoprotein cholesterol, high blood pressure and central obesity were not associated with short sleep duration.

CONCLUSION

Males with short sleep duration are positively associated with metabolic syndrome and they also exhibited a higher prevalence of hyperglycemia.

摘要

目的

在一个看似健康的中国人群中，研究睡眠时间与代谢综合征之间的关联。

方法

本研究的数据来自于台湾台南的一个健康检查中心，时间为 2006 年 10 月 1 日至 2009 年 8 月 31 日。共招募了 7100 名成年人。根据睡眠时间将受试者分为三组：短睡组（<6 小时）、正常组（6-8 小时）和长睡组（>8 小时）。

结果

不同睡眠组之间在年龄、性别、教育水平、空腹血糖以及吸烟状况和运动频率的比例方面存在显著差异。基于多因素 logistic 回归分析，短睡者在男性中与代谢综合征呈正相关（OR=1.28，95% CI：1.01-1.63），但在女性中无此相关性（OR=1.04，95% CI：0.72-1.51）。长睡者与两性的代谢综合征均无相关性。在男性中，短睡与高血糖（OR=1.39，95% CI：1.10-1.74）也独立相关。其他成分，如高三酰甘油血症、低高密度脂蛋白胆固醇血症、高血压和中心性肥胖与短睡眠时间无关。