Department of Family Medicine, Yeouido St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Nutr Diabetes. 2013 May 13;3(5):e65. doi: 10.1038/nutd.2013.8.
Epidemiological studies have repeatedly investigated the association between sleep duration and metabolic syndrome. However, the results have been inconsistent. This meta-analysis aimed to summarize the current evidence from cross-sectional and prospective cohort studies that evaluated this.
Relevant studies were identified by systematically searching the PubMed, Cochrane CENTRAL, EMBASE and PsycINFO databases through November 2012 without language restriction.
We identified 12 cross-sectional studies with 76 027 participants including 14 404 cases of metabolic syndrome, and 3 cohort studies with 2055 participants and 283 incident cases of metabolic syndrome.
For short sleep durations (<5 to 6 h), the odds ratios (OR) was 1.27 (95% confidence interval (CI)=1.10-1.48, I(2)=75.5%) in the 12 cross-sectional studies and 1.62 (95% CI=0.74-3.55, I(2)=71.4%) in the 3 cohort studies; for long sleep durations (>8 to 10 h), the OR was 1.23 (95% CI=1.02-1.49, I(2)=75.8%) in the 11 cross-sectional studies and 1.62 (95% CI=0.86-3.04, I(2)=0.0%) in the 2 cohort studies.
Short and long sleep durations are risky behaviors for increasing the risk of metabolic syndrome and thus have important public health implications, as sleep habits are amenable to behavioral interventions. The available data are sparse, and further studies, especially longitudinal studies, are needed to facilitate a better understanding of these associations.
流行病学研究已经多次调查了睡眠时间与代谢综合征之间的关联。然而，结果并不一致。本荟萃分析旨在总结目前来自横断面和前瞻性队列研究的证据，以评估这一关系。
通过系统搜索 PubMed、Cochrane CENTRAL、EMBASE 和 PsycINFO 数据库，于 2012 年 11 月前检索到无语言限制的相关研究。
我们确定了 12 项包含 76027 名参与者的横断面研究，其中包括 14404 例代谢综合征病例，以及 3 项队列研究，其中包括 2055 名参与者和 283 例代谢综合征新发病例。
对于短睡眠时间（<5 至 6 小时），12 项横断面研究的比值比（OR）为 1.27（95%置信区间（CI）=1.10-1.48，I²=75.5%），3 项队列研究的 OR 为 1.62（95% CI=0.74-3.55，I²=71.4%）；对于长睡眠时间（>8 至 10 小时），11 项横断面研究的 OR 为 1.23（95% CI=1.02-1.49，I²=75.8%），2 项队列研究的 OR 为 1.62（95% CI=0.86-3.04，I²=0.0%）。
短时间和长时间睡眠都是增加代谢综合征风险的危险因素，因此具有重要的公共卫生意义，因为睡眠习惯可以通过行为干预来改变。目前的数据还很有限，需要进一步的研究，特别是纵向研究，以更好地了解这些关联。
