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住院患者呼吸困难评分的患病率及预测价值:初步研究

Prevalence and Predictive Value of Dyspnea Ratings in Hospitalized Patients: Pilot Studies.

作者信息

Stevens Jennifer P, Baker Kathy, Howell Michael D, Banzett Robert B

机构信息

Center for Healthcare Delivery Science, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.

Department of Medicine, Division for Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.

出版信息

PLoS One. 2016 Apr 12;11(4):e0152601. doi: 10.1371/journal.pone.0152601. eCollection 2016.

Abstract

BACKGROUND

Dyspnea (breathing discomfort) can be as powerfully aversive as pain, yet is not routinely assessed and documented in the clinical environment. Routine identification and documentation of dyspnea is the first step to improved symptom management and it may also identify patients at risk of negative clinical outcomes.

OBJECTIVE

To estimate the prevalence of dyspnea and of dyspnea-associated risk among hospitalized patients.

DESIGN

Two pilot prospective cohort studies.

SETTING

Single academic medical center.

PATIENTS

Consecutive patients admitted to four inpatient units: cardiology, hematology/oncology, medicine, and bariatric surgery.

MEASUREMENTS

In Study 1, nurses documented current and recent patient-reported dyspnea at the time of the Initial Patient Assessment in 581 inpatients. In Study 2, nurses documented current dyspnea at least once every nursing shift in 367 patients. We describe the prevalence of burdensome dyspnea, and compare it to pain. We also compared dyspnea ratings with a composite of adverse outcomes: 1) receipt of care from the hospital's rapid response system, 2) transfer to the intensive care unit, or 3) death in hospital. We defined burdensome dyspnea as a rating of 4 or more on a 10-point scale.

RESULTS

Prevalence of burdensome current dyspnea upon admission (Study 1) was 13% (77 of 581, 95% CI 11%-16%). Prevalence of burdensome dyspnea at some time during the hospitalization (Study 2) was 16% (57 of 367, 95% CI 12%-20%). Dyspnea was associated with higher odds of a negative outcome.

CONCLUSIONS

In two pilot studies, we identified a significant symptom burden of dyspnea in hospitalized patients. Patients reporting dyspnea may benefit from a more careful focus on symptom management and may represent a population at greater risk for negative outcomes.

摘要

背景

呼吸困难(呼吸不适)可能与疼痛一样具有强烈的厌恶性,但在临床环境中并未常规进行评估和记录。呼吸困难的常规识别和记录是改善症状管理的第一步,还可能识别出有不良临床结局风险的患者。

目的

估计住院患者中呼吸困难及其相关风险的患病率。

设计

两项前瞻性队列研究试点。

地点

单一学术医疗中心。

患者

连续入住四个住院科室的患者:心脏病科、血液科/肿瘤科、内科和减肥手术科。

测量

在研究1中,护士记录了581名住院患者初次评估时患者报告的当前和近期呼吸困难情况。在研究2中,护士在367名患者的每个护理班次至少记录一次当前呼吸困难情况。我们描述了严重呼吸困难的患病率,并将其与疼痛进行比较。我们还将呼吸困难评分与一组不良结局进行了比较:1)接受医院快速反应系统的护理,2)转入重症监护病房,或3)住院死亡。我们将严重呼吸困难定义为10分制评分中达到4分或更高。

结果

入院时(研究1)严重当前呼吸困难的患病率为13%(581例中的77例,95%置信区间11%-16%)。住院期间某个时间点严重呼吸困难的患病率为16%(367例中的57例,95%置信区间12%-20%)。呼吸困难与不良结局的较高几率相关。

结论

在两项试点研究中,我们确定了住院患者中存在显著的呼吸困难症状负担。报告呼吸困难的患者可能会从更密切关注症状管理中受益,并且可能代表不良结局风险更高的人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a89f/4829144/15837dfd0132/pone.0152601.g001.jpg

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