Wang Yu-Xing, Yuan Ming-Zhi, Wen Zhao-Xia
Department of Radiology, Linyi People's Hospital, Linyi 276003, China.
J Cancer Res Ther. 2016 Jan-Mar;12(1):401-5. doi: 10.4103/0973-1482.163667.
The aim of this study was to investigate the value of two quantitative indicators, the apparent diffusion coefficient (ADC) and the exponent apparent diffusion coefficient (EADC), of magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in the differential diagnosis of ovarian epithelial tumors.
Clinical and MRI data from ovarian epithelial tumors were analyzed after pathology confirmation of 85 lesions from 76 cases (47 lesions from 41 benign cases; 38 lesions from 35 malignant cases). Patients underwent routine MRI examination and DWI before surgery. The average ADC and EADC values of the solid sections of the tumors were measured when the b value was 1000 s/mm 2.
The mean ADC value of the solid sections in the benign group was 1.28 ± 0.23 × 10-3 mm 2/s; the average EADC value was 27.96 ± 5.78 × 10-2. In the malignant group, the mean ADC value of the solid sections was 0.86 ± 0.17 × 10-3 mm 2/s; the average EADC value was 42.37 ± 5.96 × 10-2. When the b value was 1000 s/mm 2, there was a statistically significant difference in ADC and EADC values between benign and malignant ovarian tumors (P < 0.05).
ADC and EADC values of DWI can be used to differentiate benign and malignant ovarian epithelial tumors.
本研究旨在探讨磁共振成像（MRI）扩散加权成像（DWI）中的两个定量指标，即表观扩散系数（ADC）和指数表观扩散系数（EADC）在卵巢上皮性肿瘤鉴别诊断中的价值。
对76例患者的85个病变进行病理确诊后，分析卵巢上皮性肿瘤的临床及MRI数据（41例良性病例中的47个病变；35例恶性病例中的38个病变）。患者在手术前行常规MRI检查及DWI检查。当b值为1000 s/mm²时，测量肿瘤实性部分的平均ADC值和EADC值。
良性组实性部分的平均ADC值为（1.28±0.23）×10⁻³ mm²/s；平均EADC值为（27.96±5.78）×10⁻²。恶性组实性部分的平均ADC值为（0.86±0.17）×10⁻³ mm²/s；平均EADC值为（42.37±5.96）×10⁻²。当b值为1000 s/mm²时，良性和恶性卵巢肿瘤的ADC值和EADC值存在统计学差异（P<0.05）。
DWI的ADC值和EADC值可用于鉴别卵巢上皮性肿瘤的良恶性。
