Adachi Yasushi, Nonogaki Hirofumi, Minamiguchi Sachiko, Li Ming, Ikehara Susumu
Division of Surgical Pathology, Toyooka Hospital, Toyooka, Hyogo 668-8501, Japan; Department of Stem Cell Disorders, Kansai Medical University, Hirakata, Osaka 573-1010, Japan.
Department of Obstetrics and Gynecology, Toyooka Hospital, Toyooka 668-8501, Japan.
Mol Clin Oncol. 2016 Apr;4(4):571-573. doi: 10.3892/mco.2016.744. Epub 2016 Jan 27.
Carcinosarcoma is a rare malignant tumor of the uterus with a poor prognosis. We herein present a case of uterine carcinosarcoma in a 67-year-old woman suffering from pervaginal bleeding for 3 months, with progressive anemia. Upon biopsy of the endometrium, the tumor was diagnosed as endometrioid adenocarcinoma. Total hysterectomy, bilateral salpingo-oophorectomy and pelvic lymph node dissection were performed. The histological examination revealed that the tumor consisted of serous adenocarcinoma and sarcoma of homologous components. After the operation, chemotherapy with paclitaxel and carboplatin was administered. At approximately 3 years postoperatively, the patient remains alive and recurrence-free.
癌肉瘤是一种罕见的子宫恶性肿瘤，预后较差。我们在此报告一例67岁女性子宫癌肉瘤病例，该患者出现阴道出血3个月，并伴有进行性贫血。子宫内膜活检后，肿瘤被诊断为子宫内膜样腺癌。进行了全子宫切除术、双侧输卵管卵巢切除术和盆腔淋巴结清扫术。组织学检查显示，肿瘤由浆液性腺癌和同源成分的肉瘤组成。术后给予紫杉醇和卡铂化疗。术后约3年，患者仍存活且无复发。
