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108 例颅内动脉瘤患者采用 WEB 装置治疗的初始和中期结果。

Initial and mid-term results from 108 consecutive patients with cerebral aneurysms treated with the WEB device.

机构信息

Department of Diagnostic and Interventional Radiology and Neuroradiology, Helios General Hospital Erfurt, Erfurt, Germany.

Department of Diagnostic and Interventional Radiology, Helios General Hospital Meiningen, Meiningen, Germany.

出版信息

J Neurointerv Surg. 2017 Apr;9(4):411-417. doi: 10.1136/neurintsurg-2016-012276. Epub 2016 Apr 13.

DOI:10.1136/neurintsurg-2016-012276
PMID:27075486
Abstract

INTRODUCTION

The Woven EndoBridge (WEB) is a novel device for the treatment of wide-necked intracranial bifurcation aneurysms. The present series demonstrates our 'real-world experience' in the use of all iterations of WEB devices (available in Europe) in ruptured and unruptured aneurysms.

METHODS

We analyzed our all-inclusive cerebrovascular database for patients treated with the WEB device between October 2010 and May 2015. Anatomic and clinical results are reported for all patients.

RESULTS

One hundred and eight patients with 114 intracranial aneurysms were included in the series. Forty-seven aneurysms (41.2%) were ruptured. Eighty-six patients received angiographic and clinical follow-up after a mean of 13.4 months. One hundred and ten of 114 WEB devices (96.5%) were deployed successfully. Thromboembolic complications occurred in 11 of 110 interventions (10.0%), with a new permanent deficit in one patient. Re-rupture after WEB treatment was detected in two aneurysms (4.3%), which had both initially presented with subarachnoid hemorrhage. Angiographic follow-up revealed adequate occlusion in 68 of 90 aneurysms (75.6%). Fifteen aneurysms required retreatment.

CONCLUSIONS

This series confirms a high level of safety and efficacy of the WEB device for the treatment of wide-necked intracranial aneurysms.

摘要

介绍

编织式支架(WEB)是一种新型的治疗宽颈颅内分叉动脉瘤的装置。本系列研究展示了我们在使用所有迭代的 WEB 装置(可在欧洲获得)治疗破裂和未破裂的动脉瘤方面的“真实世界经验”。

方法

我们分析了 2010 年 10 月至 2015 年 5 月期间使用 WEB 装置治疗的所有脑血管患者的综合数据库。报告了所有患者的解剖学和临床结果。

结果

108 例患者的 114 个颅内动脉瘤被纳入本研究。47 个动脉瘤(41.2%)为破裂性。86 例患者在平均 13.4 个月后接受了血管造影和临床随访。114 个 WEB 装置中有 110 个(96.5%)成功植入。110 次干预中有 11 次(10.0%)发生血栓栓塞并发症,1 例患者出现新的永久性残疾。WEB 治疗后发现两个动脉瘤(4.3%)再次破裂,这两个动脉瘤最初均表现为蛛网膜下腔出血。血管造影随访显示 90 个动脉瘤中有 68 个(75.6%)得到充分闭塞。15 个动脉瘤需要再次治疗。

结论

本系列研究证实了 WEB 装置治疗宽颈颅内分叉动脉瘤的高安全性和有效性。

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