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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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EFFECT OF ADRENOCORTICOTROPHIC HORMONE AND CORTISONE ON THE UPTAKE OF TRITIATED THYMIDINE BY REGENERATING LIVER TISSUE IN THE WHITE RAT.促肾上腺皮质激素和可的松对白鼠再生肝组织摄取氚标记胸腺嘧啶的影响
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Effects of cortisone on regenerating rat liver.可的松对大鼠再生肝脏的影响。
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An early mitosis-determining event in regenerating rat liver and its possible mediation by prostaglandins or thromboxane.
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C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment.C-myc转录本在大鼠肝脏再生的极早期或经环己酰亚胺处理后被诱导。
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The effect of methotrexate on enzymes induced following partial hepatectomy.甲氨蝶呤对部分肝切除术后诱导酶的影响。
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Inhibition of DNA synthesis in regenerating rat liver hy hydrocortisone.
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Liver regeneration after carbon tetrachloride intoxication in the rat.大鼠四氯化碳中毒后的肝脏再生
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10
Reversal of ethanol and indomethacin-induced suppression of hepatic DNA synthesis by 16,16-dimethyl prostaglandin E2.16,16 - 二甲基前列腺素E2对乙醇和吲哚美辛所致肝DNA合成抑制的逆转作用
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糖皮质激素对大鼠部分肝切除术后肝脏再生的影响。

Effect of glucocorticoid on liver regeneration after partial hepatectomy in the rat.

作者信息

Tsukamoto I, Kojo S

机构信息

Department of Food Science and Nutrition, Nara Women's University, Japan.

出版信息

Gut. 1989 Mar;30(3):387-90. doi: 10.1136/gut.30.3.387.

DOI:10.1136/gut.30.3.387
PMID:2707640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1378464/
Abstract

The increase in activities of hepatic thymidylate synthetase (EC 2.1.1.45) and thymidine kinase (EC 2.7.1.21), which catalyse the formation of thymidylate through the de novo and salvage pathways, respectively, were significantly suppressed during liver regeneration in rats which were given glucocorticoids (hydrocortisone and dexamethasone) or indomethacin. These drugs also prevented the augment of hepatic DNA content in 24 h regenerating liver.

摘要

在给予糖皮质激素（氢化可的松和地塞米松）或吲哚美辛的大鼠肝脏再生过程中，催化分别通过从头合成途径和补救途径形成胸苷酸的肝胸苷酸合成酶（EC 2.1.1.45）和胸苷激酶（EC 2.7.1.21）的活性增加受到显著抑制。这些药物还阻止了24小时再生肝脏中肝DNA含量的增加。