远程预处理与心脏手术：心脏手术远程缺血预处理（RIPHeart）后的重新分组以及远程缺血预处理对冠状动脉旁路移植术患者临床结局的影响（ERICCA）
Remote preconditioning and cardiac surgery: regrouping after Remote Ischemic Preconditioning for Heart Surgery (RIPHeart) and Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA).
作者信息
Cheung Cherry X, Healy Donagh A, Walsh Stewart R
机构信息
1 Department of Surgery, University Hospital Waterford, Waterford, Ireland ; 2 Department of Surgery, National University of Ireland Galway, University Road, Galway, Ireland.
出版信息
J Thorac Dis. 2016 Mar;8(3):E197-9. doi: 10.21037/jtd.2016.01.81.
Abstract
Remote ischaemic preconditioning (RIPC) is an attractive cardioprotective strategy. Although results from animal studies and phase II study on humans are convincing, it cannot have a role in clinical practice until benefits in clinical outcomes are proven in phase III study. Two phase III studies were recently published [Remote Ischemic Preconditioning for Heart Surgery (RIPHeart) and Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA)] and this article discusses their design, results and implications.
摘要
远程缺血预处理（RIPC）是一种颇具吸引力的心脏保护策略。尽管动物研究和人体II期研究的结果令人信服，但在III期研究证明其对临床结局有益之前，它无法在临床实践中发挥作用。最近发表了两项III期研究[心脏手术的远程缺血预处理（RIPHeart）和远程缺血预处理对冠状动脉搭桥手术患者临床结局的影响（ERICCA）]，本文将讨论它们的设计、结果及意义。
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Remote preconditioning and cardiac surgery: regrouping after Remote Ischemic Preconditioning for Heart Surgery (RIPHeart) and Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA).远程预处理与心脏手术：心脏手术远程缺血预处理（RIPHeart）后的重新分组以及远程缺血预处理对冠状动脉旁路移植术患者临床结局的影响（ERICCA）
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