Bozkurt Ilkay, Sunbul Mustafa, Yilmaz Hava, Esen Saban, Leblebicioglu Hakan, Beeching Nicholas J
a Department of Infectious Diseases and Clinical Microbiology , Ondokuz Mayis University Medical School , Samsun , Turkey.
b Tropical and Infectious Disease Unit , Liverpool School of Tropical Medicine , Liverpool , UK.
Pathog Glob Health. 2016;110(1):9-13. doi: 10.1080/20477724.2015.1136130. Epub 2016 Feb 25.
Crimean-Congo hemorrhagic fever (CCHF) is endemic in Turkey, with peak incidence of hospital admissions in the summer months. The aim of this pilot study was to evaluate the role of the severity grading score (SGS) in predicting length of hospital stay, laboratory usage, need for blood products, and hence total costs of patients. Thirty-five patients admitted to one specialist center in Turkey in 2013 and 2014 with PCR-proven CCHF. The mean (SD) age was 55 (±14) and 63% of the patients were male, with 8 (22.9%) mortality. Patients were classified by SGS into three groups with mortality as follows: low risk (0/19); intermediate (6/14); and high (2/2). The direct hospital cost of these admissions was at least $41 740 with median (range) of $1210 ($97-$13 054) per patient. There was a significant difference between low-risk and combined (intermediate-high) risk groups as 635 (97-1500) and 2264.5 (154-13 054), respectively (p = 0.012). In conclusion, a clinical grading score can be used to predict illness severity and to predict associated health care costs.
克里米亚-刚果出血热(CCHF)在土耳其呈地方性流行,夏季住院人数发病率达到峰值。这项初步研究的目的是评估严重程度分级评分(SGS)在预测住院时间、实验室检查使用情况、血液制品需求以及患者总费用方面的作用。2013年和2014年,35例经PCR证实患有CCHF的患者入住土耳其一家专科中心。平均(标准差)年龄为55岁(±14),63%的患者为男性,8例(22.9%)死亡。根据SGS将患者分为三组,死亡率如下:低风险组(0/19);中风险组(6/14);高风险组(2/2)。这些住院患者的直接医院费用至少为41740美元,每位患者的中位数(范围)为1210美元(97 - 13054美元)。低风险组与合并(中 - 高)风险组之间存在显著差异,分别为635(97 - 1500)美元和2264.5(154 - 13054)美元(p = 0.012)。总之,临床分级评分可用于预测疾病严重程度以及相关的医疗保健费用。