Clinical Microbiology and Infectious Diseases Department, Ondokuz Mayis University School of Medicine, Samsun, Turkey.
Pathog Glob Health. 2021 Oct-Dec;115(7-8):496-498. doi: 10.1080/20477724.2021.1878450. Epub 2021 Jan 23.
As the COVID-19 pandemic continues, countries still have to struggle with their endemic diseases such as Crimean-Congo hemorrhagic fever (CCHF). Severity grading score (SGS) is a practical approach and may shed light on the course of the CCHF, whose pathogenesis is not clearly understood, and have no effective treatments. It is aimed to assess the association between SGS and acute phase reactants (APR). Laboratory-confirmed patients were categorized by severity scores, and the relationship between APR and SGS was evaluated. A significant correlation between SGS and C-reactive protein (CRP) was found ( < 0.001). High SGS was associated with mortality and high CRP levels were used to predict the mortality at the beginning of the hospital admission. To predict the outcome of the disease and for appropriate patient management, SGS and APR can be used simultaneously.
随着 COVID-19 大流行的持续，各国仍需应对其地方性疾病，如克里米亚-刚果出血热（CCHF）。严重程度分级评分（SGS）是一种实用的方法，可能有助于了解发病机制尚不清楚且无有效治疗方法的 CCHF 病程。其旨在评估 SGS 与急性时相反应物（APR）之间的关系。根据严重程度评分对实验室确诊的患者进行分类，并评估 APR 与 SGS 的关系。发现 SGS 与 C 反应蛋白（CRP）之间存在显著相关性（<0.001）。高 SGS 与死亡率相关，高 CRP 水平可用于预测住院初期的死亡率。为了预测疾病的结果并进行适当的患者管理，可以同时使用 SGS 和 APR。
