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腮腺破骨细胞样巨细胞瘤:1例经细针穿刺抽吸细胞学诊断并结合组织学和免疫组化结果的病例报告

Osteoclast-Like Giant Cell Tumor of the Parotid Gland: Report of a Case Diagnosed on Fine-Needle Aspiration Cytology With Histological and Immunohistochemical Findings.

作者信息

Elhence Poonam, Rao Meenakshi, Goyal Amit, Kumar Amit, Khera Pushpinder S, Bhattacharya Shilajit

机构信息

Department of Pathology, AIIMS, Jodhpur, Rajasthan, India.

Department of ENT, AIIMS, Jodhpur, Rajasthan, India.

出版信息

Diagn Cytopathol. 2016 Jun;44(6):548-51. doi: 10.1002/dc.23482. Epub 2016 Apr 15.

DOI:10.1002/dc.23482
PMID:27079183
Abstract

Extraosseous giant cell tumors have been described in organs like larynx, thyroid, pancreas, heart, skin, lung, colon, kidney, and soft tissues (Wu et al., Oncol Lett 2013;6:829-832). Osteoclast-like giant cell tumor of the parotid gland has been reported only rarely with the first description of primary giant cell tumour of the parotid gland (GCTPs) given in 1984 by Eusebi et al. (Am J Clin Pathol. 1984;81:666-675). However, FNAC of osteoclast-like giant cell tumor of the parotid gland has not been well described, and only one case has been reported till date (Torabinezad et al., Acta Cytol. 2006;50:80-83). Two presentations have been observed in the form of either an isolated giant cell tumor (Eusebi et al., Am J Clin Pathol. 1984;81:666-675) or tumor associated with a carcinomatous component (Yang et al., Korean J Pathol 2012;46:297-301; Pasricha et al., J Can Res Ther 2013;9:314-316). GCTPs are uncommon benign soft tissue tumors with a malignant potential. Diagn. Cytopathol. 2016;44:548-551. © 2016 Wiley Periodicals, Inc.

摘要

骨外巨细胞瘤已在喉、甲状腺、胰腺、心脏、皮肤、肺、结肠、肾脏等器官以及软组织中被描述(Wu等人,《肿瘤学快报》2013年;6:829 - 832)。腮腺破骨细胞样巨细胞瘤仅被罕见报道,1984年Eusebi等人首次描述了腮腺原发性巨细胞瘤(GCTPs)(《美国临床病理学杂志》。1984年;81:666 - 675)。然而,腮腺破骨细胞样巨细胞瘤的细针穿刺抽吸活检(FNAC)尚未得到充分描述,迄今为止仅报道了1例(Torabinezad等人,《细胞学报》。2006年;50:80 - 83)。已观察到两种表现形式,即孤立性巨细胞瘤(Eusebi等人,《美国临床病理学杂志》。1984年;81:666 - 675)或与癌性成分相关的肿瘤(Yang等人,《韩国病理学杂志》2012年;46:297 - 301;Pasricha等人,《癌症研究与治疗杂志》2013年;9:314 - 316)。GCTPs是具有恶性潜能的罕见良性软组织肿瘤。《诊断细胞病理学》。2016年;44:548 - 551。©2016威利期刊公司。

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