Ma Qing, Chang Howard Y
Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Genome Biol. 2016 Apr 14;17:68. doi: 10.1186/s13059-016-0933-0.
Single-cell RNA-seq in samples from the human neocortex demonstrate that long noncoding RNAs (lncRNAs) are abundantly expressed in specific individual brain cells, despite being hard to detect in bulk samples. This result suggests that the lncRNAs might have important functions in specific cell types in the brain.
对人类新皮层样本进行的单细胞RNA测序表明,长链非编码RNA(lncRNA)在特定的单个脑细胞中大量表达,尽管在大量样本中难以检测到。这一结果表明,lncRNA可能在大脑的特定细胞类型中具有重要功能。