Walker Christopher D, Shankaran Shivanjali
Eastern Virginia Medical School, Norfolk, VA.
Division of Infectious Diseases, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA.
Am J Infect Control. 2016 Sep 1;44(9):1050-2. doi: 10.1016/j.ajic.2016.02.018. Epub 2016 Apr 11.
Infections caused by carbapenemase-producing Klebsiella pneumoniae resistant to tigecycline, colistin, or aminoglycosides are a growing health concern. In our retrospective chart review, we noted increased resistance to colistin compared with tigecycline, despite limited prior use of colistin. This may affect the choice of presumptive antibiotics used in these hard to treat infections. Improved infection control and antimicrobial stewardship practices are essential to prevent the spread of these multidrug-resistant organisms.
由产碳青霉烯酶的肺炎克雷伯菌引起的感染，对替加环素、黏菌素或氨基糖苷类耐药，这一情况对健康的影响日益受到关注。在我们的回顾性病历审查中，我们注意到，尽管之前黏菌素的使用有限，但与替加环素相比，对黏菌素的耐药性有所增加。这可能会影响这些难以治疗的感染中经验性抗生素的选择。加强感染控制和抗菌药物管理措施对于防止这些多重耐药菌的传播至关重要。
